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New antibacterial depsidones from an ant-derived fungus Spiromastix sp. MY-1

文献类型: 外文期刊

作者: Guo, Zhi-Kai 1 ; Zhu, Wen-Yong 1 ; Zhao, Li-Xing 1 ; Chen, Yan-Chi 1 ; Li, Sui-Jun 1 ; Cheng, Ping 1 ; Ge, Hui-Ming 1 ; Tan, Ren-Xiang 1 ; Jiao, Rui-Hua 1 ;

作者机构: 1.Nanjing Univ, Inst Funct Biomol, Sch Life Sci, State Key Lab Pharmaceut Biotechnol, Nanjing 210093, Peoples R China

2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Hainan Key Lab Trop Microbe Resources, Haikou 571101, Peoples R China

3.Chinese Acad Med Sci, Inst Med Biol, Yunnan Key Lab Vaccine Res & Dev Severe Infect Dis, Kunming 650118, Peoples R China

4.Yunnan Univ, Yunnan Inst Microbiol, Kunming 650091, Peoples R China

关键词: Fungus; Spiromastix sp.; Depsidones; Phytopathogenic bacteria; Antibacterial

期刊名称:CHINESE JOURNAL OF NATURAL MEDICINES ( 影响因子:3.887; 五年影响因子:3.273 )

ISSN: 2095-6975

年卷期: 2022 年 20 卷 8 期

页码:

收录情况: SCI

摘要: Six new (1-6) and seven known depsidones (7-13) were isolated from the culture of an ant (Monomorium chinensis)-derived fungus Spiromastix sp. MY-1. Their structures were elucidated by extensive spectroscopic analysis including high resolution MS, 1D and 2D NMR data. The new bromide depsidones were obtained through supplementing potassium bromide in the fermentation medium of Spiromastix sp. MY-1. All isolated compounds showed various bioactivities against the tested phytopathogenic bacteria. Particularly, new bromide compound 4, named spiromastixone S, exhibited the strongest activity against Xanthomonas oryzae pv. oryzae with a MIC value of 5.2 mu mol.L-1.

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