Determination of Amicarbazone and Its Metabolites in Corn and Its Plant with a Modified QuEChERS by Liquid Chromatography-Tandem Mass Spectrometry
文献类型: 外文期刊
作者: Dong Mao-Feng 1 ; Bai Bing 1 ; Tang Hong-Xia 1 ; Wang Wei-Min 1 ; Zhao Zhi-Hui 1 ; Han Zheng 1 ; Song Wei-Guo 1 ;
作者机构: 1.Shanghai Acad Agr Sci, Inst Agrofood Stand & Testing Technol, Shanghai 201403, Peoples R China
关键词: Amicarbazone;Metabolites;Corn;Liquid chromatography-tandem mass spectrometry;QuEChERS
期刊名称:CHINESE JOURNAL OF ANALYTICAL CHEMISTRY ( 影响因子:1.134; 五年影响因子:0.909 )
ISSN: 0253-3820
年卷期: 2015 年 43 卷 5 期
页码:
收录情况: SCI
摘要: A modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) method was developed to analyze amicarbazone and its Metabolites residues in corn and its plant with liquid chromatography. tandem mass spectrometry (LC-MS/MS) detection. After extracted with MeCN and purified with graphite carbon black (GCB) and with C-18 as dispersive solid phase extraction, the sample was measured by LC-MS/MS equipped an Agilent EC-C-18 column with methanol-5 mmol/L ammoniumacetate as mobile phase. The linear range was 1 - 1000 mu g/L and the recoveries ranged from 85.1% - 111.0% with the relative standard deviations (RSDs) of 2.3% - 11.0%. The limit of quantification (LOQ) was 5 mu g/kg. The residues of amicarbazone (AMZ) and its metabolites (DA and ISO) were lower than the limit of detection (LOQ) in 15 samples obtained from local markets. The results showed that the method was simple, fast, and efficient for analysis of amicarbazone and its metabolites in corn matrices.
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