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Antioxidant Effects of Oats Avenanthramides on Human Serum

文献类型: 外文期刊

作者: Liu Sen 2 ; Yang Nan 1 ; Hou Zhao-hua 1 ; Yao Yang 1 ; Lue Li 3 ; Zhou Xian-rong 1 ; Ren Gui-xing 1 ;

作者机构: 1.Chinese Acad Agr Sci, Inst Crop Sci, Beijing 100081, Peoples R China

2.Shanxi Acad Agr Sci, Inst Comprehens Utilizat Agr Prod, Taiyuan 030031, Peoples R China

3.Chinese Peoples Armed Police Forces, Gen Hosp, Beijing 100039, Peoples R China

关键词: oats avenanthramides;human serum;antioxidation;SOD;MDA;LDL-C;HDL-C

期刊名称:AGRICULTURAL SCIENCES IN CHINA ( 影响因子:0.82; 五年影响因子:0.997 )

ISSN: 1671-2927

年卷期: 2011 年 10 卷 8 期

页码:

收录情况: SCI

摘要: The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study. Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo for 1 mon. Plasma lipid peroxides and antioxidant status were measured. For 8 capsules (containing 3.12 mg avenanthramides) groups, the levels of serum superoxide dismutase (SOD) and reduced glutathione hormone (GSH) were significantly increased by 8.4 and 17.9%, respectively (P<0.05), and malondialdehyde (MDA) level significantly decreased by 28.1%. The total cholesterol (TC), triglyceride (TG), and low density lipoprotein cholesterol (LDL-C) levels were lowered by 11.1, 28.1, and 15.1%, respectively (P<0.05). The high density blood lipoprotein cholesterol (HDL-C) levels in the same treat was increased by 13.2%. Based on our research, it can be concluded that oats extract containing avenanthramides possessed a high antioxidative activity on humans. It indicated that oat avenanthramides could be used to prevent hyperlipemic and angiocardiopathy.

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