Genomic sequence of an avian paramyxovirus type 1 strain isolated from Muscovy duck (Cairina moschata) in China
文献类型： 外文期刊
作者： Shi, S. -H. 1 ; Huang, Yu 1 ; Cui, S. -J. 3 ; Cheng, L. -F. 1 ; Fu, G. -H. 1 ; Li, X. 3 ; Chen, Z. 1 ; Peng, C. -X. 1 ; Lin, 1 ;
作者机构： 1.Fujian Acad Agr Sci, Inst Anim Husb & Vet, Fuzhou 350013, Fujian, Peoples R China
2.Fujian Anim Dis Control Technol Dev Ctr, Fuzhou 350013, Fujian, Peoples R China
3.Chinese Acad Agr Sci, Harbin Vet Res Inst, Harbin 150001, Heilongjiang, Peoples R China
4.China Agr Univ, Coll Vet Med, Minist Agr, Key Lab Zoonosis, Beijing 100193, Peoples R China
期刊名称：ARCHIVES OF VIROLOGY （ 影响因子：2.574； 五年影响因子：2.466 ）
ISSN： 0304-8608
年卷期： 2011 年 156 卷 3 期
页码：
收录情况： SCI
摘要： The complete sequence of an avian paramyxovirus type 1 (APMV-1) strain, FP1/02, isolated from Muscovy duck in China, was determined. Sequence analysis indicated that the complete genome of strain FP1/02 contained 15,192 nucleotides (nt), following the rule of six. The genome contained an extra 6-nt insertion in the non-coding region of the NP gene when compared with other APMV-1 strains, such as strains La Sota and Beaudette C. The cleavage site of the F protein was R-112-R-Q-K-Ra dagger"F-117, indicating that the FP1/02 strain was virulent, but the morbidity and mortality varied with the species of duck. Genotypic analysis based on the F gene revealed that APMV-1 FP1/02 was a member of genotype VII. Phylogenetic analysis showed that the FP1/02 strain shared high identity with other APMV-1 strains such as ZJ1, SF02 and NA-1 isolated from geese.
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