您好，欢迎访问中国水产科学研究院 机构知识库！
中国水产科学研究院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Genomic and biochemical analysis reveals fermented product of a putative novel Romboutsia species involves the glycometabolism of tilapia

文献类型： 外文期刊

作者： Fan, Zijian 1 ; Ke, Xiaoli 1 ; Jiang, Lijin 1 ; Zhang, Ziyue 1 ; Yi, Mengmeng 1 ; Liu, Zhigang 1 ; Cao, Jianmeng 1 ; Lu, Maixin 1 ; Wang, Miao 1 ;

作者机构： 1.Chinese Acad Fishery Sci, Key Lab Trop & Subtrop Fishery Resource Applicat &, Guangdong Prov Key Lab Aquat Anim Immunol & Sustai, Minist Agr & Rural Affairs,Pearl River Fisheries R, Guangzhou 510380, Guangdong, Peoples R China

2.Guangdong Lab Lingnan Modern Agr, Maoming Branch, Maoming 525000, Guangdong, Peoples R China

关键词： Romboutsia; tilapia; Carbohydrate; Gut microbiota; SCFAs

期刊名称：AQUACULTURE （ 影响因子：4.5； 五年影响因子：4.6 ）

ISSN： 0044-8486

年卷期： 2024 年 581 卷

页码：

收录情况： SCI

摘要： Fish have a restricted capacity to utilize carbohydrates. Gut microbiota contribute to carbohydrate degradation in the host. The connection between the intestinal microbiota and carbohydrate metabolism is not well known in fish. We found that when feed was transformed from zooplankton-based to plant-based diet, the population of genus Romboutsia in tilapia gut increased. We inferred that the abundance of the genus Romboutsia was positively correlated with dietary sugar levels. Then, a strain of genus Romboutsia was obtained and designated MY01. Strain MY01 was a novel species of Romboutsia based on its genomic analysis. Many genes involved in carbohydrate metabolism were found in its genome, including Carbohydrate Active enZymes (CAZymes) genes associated with dietary fiber fermentation. An increased quantity of short-chain fatty acids (SCFAs) and decreased quantity of carbohydrates in feed fermented with MY01 were revealed by GC-MS and HPLC analysis. Fermented feed with MY01 increased the insulin content and decreased the glucose content of tilapia serum. Our in vivo and in vitro results are the first to suggest that fermented feed with Romboutsia regulates the tilapia glycometabolism by producing SCFAs to stimulate insulin secretion, and by reducing carbohydrates content of feed simultaneously to decrease blood glucose eventually. In further, the study provides a potential source of SCFAs production.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国水产科学研究院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台