Lineage-specific gene evolution of innate immunity in Bombyx mori to adapt to challenge by pathogens, especially entomopathogenic fungi
文献类型： 外文期刊
作者： Geng, Tao 1 ; Lu, Fuping 1 ; Zhu, Feng 3 ; Wang, Shuchang 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Environm & Plant Protect Inst, Haikou 571101, Hainan, Peoples R China
2.Chinese Acad Trop Agr Sci, Sericulture Res Ctr, Haikou 571101, Hainan, Peoples R China
3.Zaozhuang Univ, Coll Life Sci, Zaozhuang 277160, Peoples R China
关键词： Bombyx mori; Antifungal; Innate immunity; Gene evolution; Immune signalling pathways
期刊名称：DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY （ 影响因子：3.636； 五年影响因子：3.654 ）
ISSN： 0145-305X
年卷期： 2021 年 123 卷
页码：
收录情况： SCI
摘要： Bombyx mori is a model species of Lepidoptera, in which 21 gene families and 220 genes have been identified as involved in immunity. However, only 45 B. mori - Drosophila melanogaster - Anopheles gambiae - Apis mellifera Tribolium castaneum 1:1:1:1:1 orthologous genes were identified. B. mori has unique immune factors not found in D. melanogaster - A. gambiae - A. mellifera - T. castaneum. Pattern recognition receptors, signal transducers and effector genes for antifungal immune responses in B. mori have evolved through expansion and modification of existing genes. This review summarizes the current knowledge of the antifungal immune responses of B. mori and focuses on the lineage-specific gene evolution used by Lepidoptera to adapt to the challenge by pathogens, especially entomopathogenic fungi.
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