The role of the intestinal microbiota in the pathogenesis of host depression and mechanism of TPs relieving depression
文献类型： 外文期刊
作者： Liu, Yang 1 ; Wu, Zufang 1 ; Cheng, Lu 3 ; Zhang, Xin 1 ; Yang, Haining 4 ;
作者机构： 1.Ningbo Univ, Coll Food & Pharmaceut Sci, Lab Food Biotechnol, Ningbo 315211, Peoples R China
2.Fujian Acad Agr Sci, Inst Qual Stand & Testing Technol Agroprod, Fuzhou 350003, Peoples R China
3.Rutgers State Univ, Dept Food Sci, Brunswick, NJ 08901 USA
4.Jiangnan Univ, Sch Biotechnol, Wuxi 214122, Jiangsu, Peoples R China
期刊名称：FOOD & FUNCTION （ 影响因子：5.396； 五年影响因子：5.536 ）
ISSN： 2042-6496
年卷期： 2021 年 12 卷 17 期
页码：
收录情况： SCI
摘要： Depression is a prevalent neuropsychiatric disease with a high recurrence rate, affecting over 350 million people worldwide. Intestinal flora disorders and gut-brain-axis (GBA) dysfunction may cause mental disorders. Alterations in the intestinal flora composition could increase the permeability of the gut barrier, activate systemic inflammation and immune responses, regulate the release and efficacy of monoamine neurotransmitters, alter the activity and function of the hypothalamic-pituitary-adrenal (HPA) axis, and modify the abundance of the brain-derived neurotrophic factor (BDNF); all of these showed a close correlation with the occurrence of depression. In addition, the disturbance of the intestinal flora is related to circadian rhythm disorders, which aggravate the symptoms of depression. Tea polyphenols (TPs) have been found to have antidepressant effects. Therefore, the close reciprocity between the intestinal flora and circadian rhythm provides a new opportunity for TPs to regulate depression relying on the intestinal flora. In this review, we discussed the relationship between intestinal flora dysbiosis and the pathogenesis of depression and the mechanism of TPs relieving depression via the GBA.
- 相关文献
作者其他论文 更多>>
-
Heterologous expression and characterization of Bacillus velezensis SW5 serine protease involved in the hydrolysis of anchovy protein
作者：Li, Na;Liu, Yang;Weng, Peifang;Wu, Zufang;Liu, Yang
关键词：Bacillus velezensis; serine protease; enzymatic properties; anchovy hydrolysis; antioxidant activity
-
A novel cold-adapted phospho-beta-galactosidase from Bacillus velezensis and its potential application for lactose hydrolysis in milk
作者：Liu, Yang;Wu, Zufang;Weng, Peifang;Zhang, Xin;Wang, Changyu;Liu, Yang;Zeng, Xiaoxiong
关键词：Bacillus velezensis SW5; Cold-adapted phospho-beta-galactosidase; Lactose hydrolysis
-
Overexpression and characterization of a novel GH4 galactosidase with beta-galactosidase activity from Bacillus velezensis SW5
作者：Li, Na;Liu, Yang;Wang, Changyu;Weng, Peifang;Wu, Zufang;Liu, Yang;Zhu, Yazhu
关键词：Bacillus velezensis; galactosidase; enzymatic properties; lactase hydrolysis
-
Cloning, expression and enzymatic characterization of a cystatin gene involved in herbivore defense in tea plant (Camellia sinensis)
作者：Zhang, Xin;Ran, Wei;Li, Xiwang;Hao, Wanjun;Sun, Xiaoling;Zhang, Xin;Ran, Wei;Li, Xiwang;Hao, Wanjun;Sun, Xiaoling;Liu, Fengjing
关键词：Cystatin; Gene clone; Expression; Camellia sinensis; Defensive role
-
Characterization of an Intracellular Alkaline Serine Protease from Bacillus velezensis SW5 with Fibrinolytic Activity
作者：Yang, Haining;Liu, Yang;Ning, Yuchang;Wang, Changyu;Zhang, Xin;Weng, Peifang;Wu, Zufang;Liu, Yang;Ning, Yuchang
关键词：
-
Pseudomonas piscis sp. nov., isolated from the profound head ulcers of farmed Murray cod (Maccullochella peelii peelii)
作者：Liu, Yang;Rao, Qiuhua;Lin, Qiu;Luo, Tuyan;Liu, Yang;Liu, Yang;Blom, Jochen
关键词：Pseudomonas piscis sp.nov; polyphasic taxonomy; head ulcers; farmed Murray cod
-
Pseudomonas ovata sp. nov., Isolated from the Skin of the Tail of Farmed Murray cod (Maccullochella peelii peelii) with a Profound Ulceration
作者：Rao, Qiuhua;Liu, Yang;Lin, Qiu;Ren, Lihua;Huang, Minmin;Tu, Jiefeng;Luo, Tuyan;Liu, Yang;Chen, Can
关键词：
