Polyphenol Profile and In Vitro Antioxidant and Enzyme Inhibitory Activities of Different Solvent Extracts of Highland Barley Bran
文献类型： 外文期刊
作者： Zhang, Wengang 1 ; Lan, Yongli 1 ; Dang, Bin 2 ; Zhang, Jie 2 ; Zheng, Wancai 2 ; Du, Yan 4 ; Yang, Xijuan 2 ; Li, Zhonghong 1 ;
作者机构： 1.Northwest A&F Univ, Coll Food Sci & Engn, Yangling 712100, Peoples R China
2.Qinghai Acad Agr & Forestry Sci, Lab Res & Utilizat Qinghai Tibet Plateau Germplasm, Qinghai Tibetan Plateau Key Lab Agr Prod Proc, Xining 810016, Peoples R China
3.Qinghai Univ, Acad Agr & Forestry Sci, Xining 810016, Peoples R China
4.Qinghai Huashi Sci & Technol Investment Management, Qinghai Prov Highland Barley Resources Comprehens, Xining 810016, Peoples R China
关键词： highland barley bran; phenolic compounds; antioxidant activity; alpha-glucosidase; alpha-amylase
期刊名称：MOLECULES （ 影响因子：4.6； 五年影响因子：4.9 ）
ISSN：
年卷期： 2023 年 28 卷 4 期
页码：
收录情况： SCI
摘要： Five different solvent extracts of highland barley bran were analyzed and compared for their polyphenol profile, antioxidant activity, and alpha-glucosidase and alpha-amylase inhibitory activities. The highland barley bran acetone extract had the highest total phenolic content, total flavonoid content, and antioxidant capacity. It was followed by the methanol and ethanol extracts, while n-butanol and ethyl acetate extracts exhibited lower measured values. Diosmetin, luteolin, protocatechuic acid, vanillic acid, ferulic acid, phlorogucinol, diosmin, isoquercitrin, catechin, and isovitexin were among the most abundant phenolic compounds identified in different solvent extracts, and their concentrations varied according to the solvent used. The highest alpha-glucosidase and alpha-amylase inhibitory activity were observed in the ethyl acetate extract of highland barley bran, followed by the acetone and methanol extracts. In contrast, n-butanol and ethanol extracts exhibited lower measured values. The different solvent extracts were effective inhibitors for alpha-glucosidase and alpha-amylase with activity reaching to 34.45-94.32% and 22.08-35.92% of that of positive control acarbose, respectively. There were obvious correlations between the phenolic content and composition of different solvent extracts and their in vitro antioxidant activity, alpha-glucosidase inhibition activity and alpha-amylase inhibition activity. Black barley bran is an excellent natural raw material for developing polyphenol-rich functional foods and shows good antioxidant and hypoglycemic potential to benefit human health.
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