文献类型： 外文期刊
作者： Liang, Juntong 1 ; Liu, Xian 2 ; Yang, Peng 1 ; Yao, Zhi 1 ; Qu, Kaixing 3 ; Wang, Hongli 4 ; Zhang, Zijing 5 ; Liang, Huifeng 4 ; Cheng, Baowei 4 ; Li, Zhiming 2 ; Ru, Baorui 2 ; Zhang, Jicai 3 ; Qi, Zengfang 4 ; Wang, Eryao 5 ; Lei, Chuzhao 1 ; Chen, Hong 1 ; Huang, Bizhi 3 ; Huang, Yongzhen 1 ;
作者机构： 1.Northwest A&F Univ, Coll Anim Sci & Technol, 22 Xinong Rd, Yangling 712100, Shaanxi, Peoples R China
2.Henan Prov Anim Husb Gen Stn, Zhengzhou, Peoples R China
3.Yunnan Acad Grassland & Anim Sci, Kunming, Yunnan, Peoples R China
4.Jiaxian Anim Husb Bur, Jiaxian, Peoples R China
5.Henan Acad Agr Sci, Inst Anim Husb & Vet Sci, Zhengzhou, Peoples R China
关键词： GAL3ST1 gene; copy number variations (CNVs); growth traits; association analysis; Chinese cattle
期刊名称：ANIMAL BIOTECHNOLOGY （ 影响因子：2.141； 五年影响因子：1.92 ）
ISSN： 1049-5398
年卷期：
页码：
收录情况： SCI
摘要： Copy number variation (CNV) is a type of genomic structural variation, and the research on it has flourished in recent years. According to the high-throughput sequencing data, we found that the copy number variation region of the GAL3ST1 gene was correlated with the growth traits of bovine. It is significant that we study the CNV of GAL3ST1 gene and process the association analysis between results of Q-PCR and growth traits of Chinese cattle. In this research, SPSS software was used to detect the distribution of GAL3ST1 gene copy number in four cattle breeds and the correlation of growth traits was analyzed. Correlation analysis showed that GAL3ST1 CNV had positive effects on some growth traits of bovine (p < 0.05). In addition, the study detects the expression of GAL3ST1 gene in different tissues of Xia'nan cattles on mRNA level. The result showed that GAL3ST1 gene has different expression conditions in different tissues, results showed that the expression level was high in intestine and low in liver tissue. In a word, we speculated that the GAL3ST1 gene can be used as a molecular marker and this study confirmed that the CNV of it can provide theoretical basis for molecular breeding of cattle in China.
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