文献类型： 外文期刊
作者： Zhou, Lingbo 1 ; Wang, Can 1 ; Gao, Xu 1 ; Ding, Yanqing 1 ; Cheng, Bin 1 ; Zhang, Guobing 1 ; Cao, Ning 1 ; Xu, Yan 1 ; Sha 1 ;
作者机构： 1.Guizhou Acad Agr Sci, Inst Upland Food Crops, Guiyang 550006, Guizhou, Peoples R China
关键词： Sorghum; Hongyingzi; Genome-wide variations analysis; Whole-genome resequencing technology
期刊名称：HEREDITAS （ 影响因子：3.271； 五年影响因子：2.807 ）
ISSN： 1601-5223
年卷期： 2020 年 157 卷 1 期
页码：
收录情况： SCI
摘要： Background Hongyingzi is a sorghum (Sorghum bicolor L. Moench) cultivar for brewing Moutai liquor. For an overall understanding of the whole genome of Hongyingzi, we performed whole-genome resequencing technology to reveal its comprehensive variations. Results Compared with the BTx623 reference genome, we uncovered 1,885,774 single nucleotide polymorphisms (SNPs), 309,381 small fragments insertions and deletions (Indels), 31,966 structural variations (SVs), and 217,273 copy number variations (CNVs). These alterations conferred 29,614 gene variations. It was also predicted that 35 gene variations were related to the multidrug and toxic efflux (MATE) transporter, chalcone synthase (CHS), ATPase isoform 10 (AHA10) transporter, dihydroflavonol-4-reductase (DFR), the laccase 15 (LAC15), flavonol 3 '-hydroxylase (F3 ' H), flavanone 3-hydroxylase (F3H), O-methyltransferase (OMT), flavonoid 3 ' 5 ' hydroxylase (F3 ' 5 ' H), UDP-glucose:sterol-glucosyltransferase (SGT), flavonol synthase (FLS), and chalcone isomerase (CHI) involved in the tannin synthesis. Conclusions These results would provide theoretical supports for the molecular markers developments and gene function studies related to the tannin synthesis, and the genetic improvement of liquor-making sorghum based on the genome editing technology.
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