文献类型： 外文期刊
作者： Bergmann, S. M. 1 ; Jin, Y. 1 ; Franzke, K. 1 ; Grunow, B. 2 ; Wang, Q. 3 ; Klafack, S. 1 ;
作者机构： 1.Friedrich Loeffler Inst, Inst Infectol, OIE & Natl Reference Lab KHVD, Sudufer 10, D-17493 Greifswald, Germany
2.Leibniz Inst Farm Anim Biol FBN, Inst Muscle Biol & Growth, Jr Res Grp Fish Growth Physiol, Dummerstorf, Germany
3.Chinese Acad Fishery Sci, Peal River Fisheries Res Inst, Key Lab Aquat Anim Immune Technol, Key Lab Fishery Drug Dev,Minist Agr, Guangzhou, Peoples R China
4.Ernst Moritz Arndt Univ Greifswald, Inst Med Biochem & Mol Biol, Greifswald, Germany
关键词： aquaculture; diseases; fish (live); genetic; KHV; KHVD; viruses
期刊名称：JOURNAL OF APPLIED MICROBIOLOGY （ 影响因子：3.772； 五年影响因子：3.963 ）
ISSN： 1364-5072
年卷期： 2020 年 129 卷 1 期
页码：
收录情况： SCI
摘要： Over the last years, there has been an enormous increase in the knowledge on koi herpesvirus (KHV), koi herpesvirus disease (KHVD), pathogenesis and virus variants. Different KHV lineages have clearly been identified, possible genomic changes during replication in different cell cultures at different temperatures but also in several hosts have been identified, a persistent stage of infection has been specified and it has been shown that infection with KHV is not host specific at all, but KHVD is. Additionally, it has been shown that it is possible to combat KHVD by immunization with inactivated and attenuated live vaccines using different delivery systems but also to benefit from alternative treatments with e.g. exopolysaccharids obtained fromArthrospira platensis.
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