Prevalence of pathogens harbouring mobile antimicrobial resistance genes and virulence factors in retail beef and mutton
文献类型： 外文期刊
作者： Liu, Ying 1 ; Cui, Yifang 2 ; Peng, Wenjing 1 ; Huang, Baoyong 3 ; Ma, Lichao 1 ; Zheng, Min 1 ; Ding, Shuangyang 4 ; Zhu 1 ;
作者机构： 1.China Agr Univ, Coll Vet Med, Beijing Adv Innovat Ctr Food Nutr & Human Hlth, Beijing 100193, Peoples R China
2.Beijing Acad Agr & Forestry Sci, Inst Anim Sci & Vet Med, Beijing Key Lab Prevent & Control Infect Dis Live, Beijing 100097, Peoples R China
3.Beijing Municipal Stn Agroenvironm Monitoring, Beijing 100026, Peoples R China
4.China Agr Univ, Coll Vet Med, Natl Ctr Vet Drug Safety Evaluat, Beijing 100193, Peoples R China
5.China Agr Univ, Coll Vet Med, Beijing Key Lab Detect Technol Anim Derived Food, Beijing 100193, Peoples R China
6.China Agr Univ, Coll Vet Med, Beijing Lab Food Qual & Safety, Beijing 100193, Peoples R China
关键词： foodborne pathogen; antimicrobial resistance; bacterial toxin; meat
期刊名称：FEMS MICROBIOLOGY LETTERS （ 影响因子：2.742； 五年影响因子：2.856 ）
ISSN： 0378-1097
年卷期： 2020 年 367 卷 12 期
页码：
收录情况： SCI
摘要： Food safety is always a global issue, due to the increased dissemination of antimicrobial resistance and food poisoning related to foodborne bacterial pathogens. The purpose of this study was to assess the risk of potential foodbome bacteria of beef and mutton in retail stores. A total of 134 samples were collected from 24 local markets in Beijing, including raw and cooked beef or mutton, as well as samples derived from the corresponding environment and human beings. We obtained 674 isolates, of which Klebsiella spp. and Staphylococcus spp. were the dominant bacterial species in the meat samples and the environmental samples, respectively. Additionally, environmental bacteria are common in samples from different sources. Based on the results of antimicrobial sensitivity testing, resistance to tetracycline (with a resistance rate of 47.40%), amoxicillin + clavulanate (47.13%) and erythromycin (28.03%) were the major resistant phenotypes. According to the whole genome analysis, the extended spectrum beta-lactamase genes harboured by two K. pneumoniae strains isolated from cooked and raw beef were located on mobile elements. The major toxin genes of Bacillus cereus and adhesion- or invasion-related virulence factors were also shared among isolates from different sources. These factors pose potential risks to public health and need attention.
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