您好，欢迎访问广东省农业科学院 机构知识库！
广东省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Genomic characterization and phylogenetic analysis of a novel Nairobi sheep disease genogroup Orthonairovirus from ticks, Southeastern China

文献类型： 外文期刊

作者： Zhang, Xu 1 ; Li, Hang-Yuan 1 ; Shao, Jian-Wei 1 ; Pei, Ming-Chao 1 ; Cao, Chong 2 ; Huang, Fu-Qiang 1 ; Sun, Ming-Fei 4 ;

作者机构： 1.Foshan Univ, Sch Life Sci & Engn, Foshan, Peoples R China

2.Fujian Prov Key Lab Prevent & Control Anim Infect, Longyan, Peoples R China

3.Longyan Univ, Key Lab Prevent Vet Med & Biotechnol, Longyan, Peoples R China

4.Zhaoqing Maoming Branch Ctr, Guangdong Lab Lingnan Modern Agr Sci & Technol, Zhaoqing, Peoples R China

5.Key Lab Livestock Dis Prevent Guangdong Prov, Guangzhou, Peoples R China

6.Minist Agr & Rural Affairs, Key Lab Avian Influenza & Other Major Poultry Dis, Guangzhou, Peoples R China

7.Guangdong Acad Agr Sci, Inst Anim Hlth, Guangzhou, Peoples R China

关键词： Meihua Mountain virus; novel Orthonairovirus; NSD genogroup; metatranscriptomics; China

期刊名称：FRONTIERS IN MICROBIOLOGY （ 影响因子：6.064； 五年影响因子：6.843 ）

ISSN：

年卷期： 2022 年 13 卷

页码：

收录情况： SCI

摘要： The increasing prevalence and transmission of tick-borne diseases, especially those emerging ones, have posed a significant threat to public health. Thus, the discovery of neglected pathogenic agents carried and transmitted by ticks is urgently needed. Using unbiased high-throughput sequencing, a novel Orthonairovirus designated as Meihua Mountain virus (MHMV), was identified in bloodsucking ticks collected from cattle and wild boars in Fujian province, Southeastern China. The full-length genome was determined by RT-PCR and RACE. Genomic architecture of MHMV shares typical features with orthonairoviruses. Phylogenetic analyses suggested that MHMV is clustered into the Nairobi sheep disease (NSD) genogroup of the genus Orthonairovirus and is closely related to the Hazara virus. The RdRp, GPC, and N protein of MHMV shares 62.3%-83.5%, 37.1%-66.1%, and 53.4%-77.3% amino acid identity with other NSD genogroup viruses, respectively, representing a novel species. The overall pooled prevalence of MHMV in ticks was 2.53% (95% CI: 1.62%-3.73%, 22 positives of 134 tick pools), with 7.38% (95% CI: 3.84%-12.59%, 11 positives of 18 pools) in Haemaphysalis hystricis, 6.02% (95% CI: 1.85%-14.22%, four positives of eight pools) in H. formosensis, 25.03% (95% CI: 9.23%-54.59%, six positive of eight pools) in Dermacentor taiwanensis, and 0.16% (95% CI: 0.01%-0.72%, one positive of 100 pools) in Rhipicephalus microplus. This study presented the first report of tick-carried Orthonairovirus in Fujian province and highlighted the broad geographic distribution and high genetic diversity of orthonairoviruses in China.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：广东省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台