Development of a reliable UHPLC-MS/MS method for simultaneous determination of zearalenone and zearalenone-14-glucoside in various feed products
文献类型： 外文期刊
作者： Zhang, Zhiqi 1 ; Cai, Yaling 1 ; Fan, Kai 1 ; Huang, Qingwen 1 ; Zhao, Xiuying 1 ; Cao, Haojie 1 ; Zhao, Zhihui 1 ; Tangni, Emmanuel K. 2 ; Han, Zheng 1 ;
作者机构： 1.Shanghai Acad Agr Sci, Inst Agrofood Stand & Testing Technol, Shanghai, Peoples R China
2.Organ Contaminants & Addit, Chem & Phys Hlth Risks, Brussels, Belgium
关键词： zearalenone; zearalenone-14-glucoside; ultra-high-performance liquid chromatography-tandem mass spectrometry; HLB cartridges; feed products
期刊名称：FRONTIERS IN CHEMISTRY （ 影响因子：5.545； 五年影响因子：5.869 ）
ISSN： 2296-2646
年卷期： 2022 年 10 卷
页码：
收录情况： SCI
摘要： A reliable ultra-high-performance liquid chromatography-tandem mass spectrometry method (UHPLC-MS/MS) was developed for the simultaneous determination of two mycotoxins, that is, zearalenone (ZEN) and zearalenone-14-glucoside (ZEN-14G) in formula feed, concentrated feed, and premixed feed products. An improved sample pretreatment was achieved with the hydrophilic-lipophilic balance (HLB) cartridges efficiently removing the impurities and enriching the target analytes in different feeds. The critical parameters affecting the performance of the solid-phase extraction (SPE) procedure were carefully optimized, and 20% acetonitrile in water as the loading solution, 50% methanol in water as the washing solvent, and 5 ml of methanol as the elution solvent yielded the optimal purification efficiencies. The established method was thoroughly validated in terms of linearity (R (2) & GE; 0.999), sensitivity (limit of quantification in the range of 0.50-5.00 mu g kg(-1)), recovery (89.35 & PLUSMN; 2.67% to 110.93 & PLUSMN; 1.56%), and precision (RSD, 3.00-14.20%), and it was then successfully applied to investigate a total of 60 feed samples. Among them, 50 samples were found to be contaminated with ZEN (an incidence of 83.3%) at levels ranging from 0.63 to 615.24 mu g kg(-1), whereas 22 samples were contaminated with ZEN-14G (an incidence of 36.7%) in the range of 0.89-15.31 mu g kg(-1). The developed method proved to be a specific and reliable tool for intensive monitoring of ZEN and ZEN-14G in complex feed matrices.
- 相关文献
作者其他论文 更多>>
-
Preparation and characterization of the aflatoxin B1 purity certified reference material (GBW (E) 100599)
作者：Guo, Wenbo;Li, Zenghe;Guo, Wenbo;Meng, Jiajia;Wang, Xinyi;Li, Jianchi;Niu, Xueke;Zhao, Zhihui;Han, Zheng;Guo, Wenbo;Niu, Xueke
关键词：aflatoxin B1; Mass balance method; Quantitative nuclear magnetic resonance; Uncertaintity; Purity certified reference material
-
Assessing Seasonal Effects on Identification of Cultivation Methods of Short-Growth Cycle Brassica chinensis L. Using IRMS and NIRS
作者：Liu, Xing;Fan, Kai;Lu, Yangyang;Zhao, Hong;Rao, Qinxiong;Geng, Hao;Chen, Yijiao;Song, Weiguo;Liu, Xing;Fan, Kai;Lu, Yangyang;Zhao, Hong;Rao, Qinxiong;Geng, Hao;Chen, Yijiao;Song, Weiguo;Rogers, Karyne Maree;Rogers, Karyne Maree
关键词：Brassica chinensis L.; seasonal effect; stable isotope; NIRS; cultivation method; PLS-DA
-
Screening and dietary exposure assessment of T-2 toxin and its modified forms in commercial cereals and cereal-based products in Shanghai
作者：Guo, Wenbo;Feng, Disen;Yang, Xianli;Zhao, Zhihui;Yang, Junhua;Guo, Wenbo
关键词：T-2 toxin; Modified mycotoxins; Trichothecenes; UPLC-MS/MS; Cereals and cereal-based products; Dietary exposure assessment
-
Perspective Accelerated photodegradation of T-2 toxin over magnetic recyclable ZnO/ CaFe 2 O 4 nanocomposite with a p-n based Z-scheme heterojunction architecture
作者：Huang, Qingwen;Lou, Xiuping;Nie, Dongxia;Zhao, Zhihui;Fan, Kai;Guo, Wenbo;Meng, Jiajia;Han, Zheng;Lou, Xiuping;Han, Zheng;Liu, Zheyuan
关键词：T-2 toxin; Photocatalytic degradation; Z-scheme; p-n heterojunction
-
Molecularly imprinted polymer-based electrochemical sensor for rapid detection of masked deoxynivalenol with Mn-doped CeO2 nanozyme as signal amplifier
作者：Nie, Dongxia;Zhu, Xueting;Liu, Minghui;Cheng, Meng;Fan, Kai;Zhao, Zhihui;Huang, Qingwen;Han, Zheng;Zhang, Xiaolin
关键词：Deoxynivalenol-3-glucoside; Molecularly imprinted polymer; Electrochemical sensor; Mn-CeO 2; Nanozyme
-
Antifungal Activity and Action Mechanisms of 2,4-Di-tert-butylphenol against Ustilaginoidea virens
作者：Fan, Kai;Yu, Yinan;Hu, Zheng;Qian, Shen'an;Zhao, Zhihui;Meng, Jiajia;Zheng, Simin;Huang, Qingwen;Zhang, Zhiqi;Nie, Dongxia;Han, Zheng;Yu, Yinan;Zheng, Simin;Han, Zheng
关键词：Ustilaginoidea virens; 2,4-di-tert-butylphenol; antifungal activity; inhibitory mechanism
-
Reduced graphene oxide-zinc iron oxide nanomaterial as selective dispersive solid-phase extraction sorbent for extraction and enrichment of aflatoxins from milk combined with UHPLC-MS/MS analysis
作者：Tanveer, Zafar Iqbal;Xu, Tengfei;Chen, Yong;Liu, Xuesong;Wu, Yongjiang;Huang, Qingwen;Han, Zheng
关键词：Aflatoxins; Milk; Dispersive solid phase extraction; Reduced graphene oxide; UHPLC-MS/MS
