Hawthorn (Crataegus pinnatifida Bunge) polysaccharide improves the adaptability of crucian carp (Carassius auratus) to high alkalinity by regulating immunity, intestinal microbiota, and intestinal metabolomics
文献类型： 外文期刊
作者： Luo, Liang 1 ; Meng, Xianwei 1 ; Wang, Shihui 1 ; Zhang, Rui 1 ; Guo, Kun 1 ; Wang, Wei 2 ; Zhao, Zhigang 1 ;
作者机构： 1.Chinese Acad Fishery Sci, Heilongjiang River Fisheries Res Inst, Key Lab Cold Water Fish Germplasm Resources & Mult, Harbin 150070, Peoples R China
2.Harbin Inst Technol, Sch Environm, State Key Lab Urban rural Water Resource & Environ, Harbin 150090, Peoples R China
关键词： Hawthorn polysaccharide; Carbonate alkalinity; Immune; Intestinal microbiota; Intestinal metabolomics
期刊名称：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES （ 影响因子：8.5； 五年影响因子：8.7 ）
ISSN： 0141-8130
年卷期： 2025 年 320 卷
页码：
收录情况： SCI
摘要： Hawthorn (Crataegus pinnatifida Bunge) polysaccharide (HP) is one of the most important active ingredients in hawthorn and has antioxidant and immunomodulatory effects. However, HP is rarely used in aquaculture research. High alkalinity adversely affects the growth and development of aquatic organisms; therefore, new feed additives that eliminate the adverse effects high alkalinity are warranted. Therefore, in this study, we investigated the effects of HP on crucian carp under carbonate stress. HP decreased of malondialdehyde content by increasing total antioxidant capacity through up-regulation of superoxide dismutase, catalase, and glutathione peroxidase. Increased serum lysozyme and acid phosphatase activities, decreased serum alkaline phosphatase activity, and altered tumor necrosis factor-alpha (tnf-alpha), interleukin (il-10, il-8), and transforming growth factor-beta (tgf-(1) mRNA expression. This improved the antioxidant properties and immune capacity of crucian carp. Additionally, HP altered the species richness and structure of the crucian carp intestinal flora, reduced the abundance of harmful Proteobacteria, Actinobacteria, and Bacteroidetes, and increased the abundance of beneficial Firmicutes. Using liquid chromatography-mass spectrometry analysis, 168 different metabolites were detected, and alanine, aspartate, and glutamate metabolism were the most important metabolic pathways. Therefore, adding HP to feed alleviated body damage caused by alkalinity stress in crucian carp. Thus, this study provides new insights into the effects of HP on organisms in aquaculture.
- 相关文献
作者其他论文 更多>>
-
Effect of environmental factors on the control of milky disease in Chinese mitten crab (Eriocheir sinensis)
作者：Zhang, Rui;Zhao, Zhigang;Guo, Kun;Wang, Shihui;Luo, Liang;Zhang, Rui;Zhao, Zhigang;Guo, Kun;Wang, Shihui;Luo, Liang;Zhao, Xu;Deng, Xiangyi
关键词：Eriocheir sinensis; Metschnikowia bicuspidata; disease control; microbial flora; temperature; alkali pH
-
Assessment of the bioflocculant production and safety properties of Metabacillus hrfriensis sp. nov. based on phenotypic and whole-genome sequencing analysis
作者：Zhang, Rui;Zhao, Zhigang;Luo, Liang;Wang, Shihui;Guo, Kun;Xu, Wei;Zhang, Rui;Zhao, Zhigang;Luo, Liang;Wang, Shihui;Guo, Kun;Xu, Wei
关键词：Bioflocculants; EPS; Bioflocculant-production bacteria; Safety assessment; Metabacillus
-
Rational Design of Alginate Lyase AlgL3199 for Thermal Stability and Specific Activity Enhancement
作者：Chen, Zhifang;Hao, Jianhua;Guo, Yingying;Zhu, Tiantian;Sun, Jingjing;Wang, Wei;Jiang, Chengcheng;Wang, Haiying;Chen, Zhifang;Hao, Jianhua
关键词：alginate lyase; thermal stability; site-directedmutagenesis; molecular docking
-
Computation and analysis of phenotypic parameters of Scylla paramamosain based on YOLOv11-DYPF keypoint detection
作者：Wu, Chong;Zhang, Shengmao;Wang, Wei;Wu, Zuli;Yang, Shenglong;Chen, Wei;Wu, Chong;Zhang, Shengmao;Zhang, Shengmao
关键词：Scylla paramamosain; Mud crab; Keypoint detection; YOLOv11; Multi-scale fusion; Dynamic upsampling; Support vector regression (SVR)
-
Screening and Characterization of Marine Bacillus atrophaeus G4 Protease and Its Application in the Enzymatic Hydrolysis of Sheep (Ovis aries) Placenta for the Preparation of Antioxidant Peptides
作者：Wang, Wei;Peng, Guoqing;Sun, Jingjing;Jiang, Chengcheng;Hao, Jianhua;Hao, Jianhua;Zhang, Xiu
关键词：protease;
Bacillus atrophaeus ; sheep (Ovis aries ) placenta; characterization; enzymatic hydrolysis; antioxidation -
Comparative analysis of morphological characteristics and nutritional quality in wild-caught and pond-reared female mud crab, Scylla paramamosain
作者：Jiang, Xiaodong;Liu, Minhai;Lin, Zhihua;Zheng, Xiafei;Jiang, Xiaodong;Liu, Minhai;Lin, Zhihua;Zheng, Xiafei;Wang, Wei
关键词：Scylla paramamosain; Wild-caught; Pond-reared; Morphometric analyses; Nutritional quality
-
Silver carp by-product hydrolysate: A promising mucin substitute for stimulating Akkermansia muciniphila growth and metabolic activity
作者：Zhang, Huijuan;Zhang, Rui;Feng, Ruifang;Luo, Yongkang;Hong, Hui;Tan, Yuqing;Chen, Shengjun;Chang, Sam K. C.
关键词：Akkermansia muciniphila; Silver carp by-products; Medium optimization; Metabolite profiles
