Bactericidal activity of grass carp Ctenopharyngodon idella C9-deficient serum against Aeromonas hydrophila
文献类型： 外文期刊
作者： Ji, C. 1 ; Li, A. H. 1 ; Xie, J. 3 ; Zhang, D. F. 1 ; Liu, J. Y. 1 ;
作者机构： 1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Chinese Acad Fishery Sci, Freshwater Fisheries Res Ctr, Minist Agr, Wuxi 214081, Peoples R China
关键词： bacterial % survival;innate immune system;membrane attack complex;rabbit anti-C9 sera
期刊名称：JOURNAL OF FISH BIOLOGY （ 影响因子：2.051； 五年影响因子：2.25 ）
ISSN： 0022-1112
年卷期： 2011 年 79 卷 7 期
页码：
收录情况： SCI
摘要： Neutralizing complement C9 in grass carp Ctenopharyngodon idella sera with rabbit anti-C9 sera against fish complement C9, demonstrated that bactericidal activity against Aeromonas hydrophila of the C9-deficient fish sera was greatly impaired. These results indicated that the fish complement C9 plays a key role in pathogen killing through the lytic pathway. (C) 2011 The Authors Journal of Fish Biology (C) 2011 The Fisheries Society of the British Isles
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