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Antitumor Peptides from Marine Organisms

文献类型： 外文期刊

作者： Zheng, Lan-Hong 3 ; Wang, Yue-Jun 3 ; Sheng, Jun 3 ; Wang, Fang 3 ; Zheng, Yuan 3 ; Lin, Xiu-Kun 1 ; Sun, Mi 3 ;

作者机构： 1.Capital Med Univ, Dept Pharmacol, Beijing 100069, Peoples R China

2.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China

3.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao 266071, Peoples R China

关键词： antitumor;peptides;marine organisms

期刊名称：MARINE DRUGS （ 影响因子：5.118； 五年影响因子：5.951 ）

ISSN： 1660-3397

年卷期： 2011 年 9 卷 10 期

页码：

收录情况： SCI

摘要： The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new antitumor agents in the field of the development of marine bioactive substances. In this review, the progress on studies of antitumor peptides from marine sources is provided. The biological properties and mechanisms of action of different marine peptides are described; information about their molecular diversity is also presented. Novel peptides that induce apoptosis signal pathway, affect the tubulin-microtubule equilibrium and inhibit angiogenesis are presented in association with their pharmacological properties. It is intended to provide useful information for further research in the fields of marine antitumor peptides.

  • 相关文献

[1]Targeting cellular apoptotic pathway with peptides from marine organisms. Zheng, Lanhong,Zheng, Yuan,Sheng, Jun,Ji, Xiaofeng,Sun, Mi,Lin, Xiukun,Wu, Ning,Liu, Ming.

[2]Polycyclic aromatic hydrocarbons in surface sediments and marine organisms from the Daya Bay, South China. Sun, Run-Xia,Lin, Qin,Ke, Chang-Liang,Du, Fei-Yan,Gu, Yang-Guang,Sun, Run-Xia,Lin, Qin,Ke, Chang-Liang,Du, Fei-Yan,Gu, Yang-Guang,Sun, Run-Xia,Lin, Qin,Ke, Chang-Liang,Du, Fei-Yan,Gu, Yang-Guang,Sun, Run-Xia,Luo, Xiao-Jun,Mai, Bi-Xian,Cao, Kun.

[3]The antitumor and antioxidative activities of polysaccharides isolated from Isaria farinosa B05. Jiang, Yan-hua,Jiang, Xiao-lu,Wang, Peng,Mou, Hai-jin,Hu, Xiao-ke,Liu, Shu-qing,Jiang, Yan-hua. 2008

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