文献类型： 外文期刊

作者： Zhang, Bingzhou ¹ ; Qing, Jie ¹ ; Yan, Zhong ¹ ; Shi, Yuntong ¹ ; Wang, Zewei ¹ ; Chen, Jing ¹ ; Li, Junxian ¹ ; Li, Shuangxi ¹ ; Wu, Weisheng ¹ ; Hu, Xiaofang ¹ ; Li, Yang ¹ ; Zhang, Xiaoyang ¹ ; Wu, Lili ¹ ; Zhu, Shouyue ¹ ; Yan, Zheng ¹ ; Wang, Yongquan ¹ ; Guo, Xiaoli ³ ; Yu, Ligen ³ ; Li, Xiaowen ¹ ;

作者机构： 1.Shandong New Hope Liuhe Agr & Anim Husb Technol Co, NHLH Acad Swine Res, Dezhou 253034, Peoples R China

2.Xiajin New Hope Liuhe Agr & Anim Husb Co Ltd, Dezhou 253200, Peoples R China

3.Beijing Acad Agr & Forestry Sci, Res Ctr Informat Technol, Beijing, Peoples R China

4.China Agr Res Syst Yangling Comprehens test Stn, Xianyang 712100, Peoples R China

5.Shandong Engn Lab Pig & Poultry Hlth Breeding & Di, Qingdao, Peoples R China

关键词： PEDV; Prevalence; Immunization strategy; The duration of PED epidemic; Economic evaluation model

期刊名称：PORCINE HEALTH MANAGEMENT （ 影响因子：3.4； 五年影响因子：3.6 ）

ISSN：

年卷期： 2023 年 9 卷 1 期

页码：

收录情况： SCI

摘要： BackgroundPorcine epidemic diarrhea (PED) is a contagious intestinal disease caused by porcine epidemic diarrhea virus (PEDV) characterized by vomiting, diarrhea, anorexia, and dehydration, which has caused huge economic losses around the world. However, it is very hard to find completely valid approaches to control the transmission of PEDV. At present, vaccine immunity remains the most effective method. To better control the spread of PED and evaluate the validity of different immunization strategies, 240 PED outbreak cases from 577 swine breeding farms were collected and analyzed. The objective of the present study was to analyze the epidemic regularity of PEDV and evaluate two kinds of different immunization strategies for controlling PED.ResultsThe results showed that the main reasons which led to the outbreak of PED were the movement of pig herds between different pig farms (41.7%) and delaying piglets from the normal production flow (15.8%). The prevalence of PEDV in the hot season (May to October) was obviously higher than that in the cold season (January to April, November to December). Results of different vaccine immunity cases showed that immunization with the highly virulent live vaccine (NH-TA2020 strain) and the commercial inactivated vaccine could significantly decrease the frequency of swine breeding farms (5.9%), the duration of PED epidemic (1.70 weeks), and the week batches of dead piglets (0.48 weeks weaned piglets), compared with immunization with commercial attenuated vaccines and inactivated vaccine of PED. Meanwhile, immunization with the highly virulent live vaccine and the commercial inactivated vaccine could bring us more cash flows of Y ̶275,274 per year than immunization with commercial live attenuated vaccine and inactivated vaccine in one 3000 sow pig farm within one year.ConclusionTherefore, immunization with highly virulent live vaccine and inactivated vaccine of PED is more effective and economical in the prevention and control of PED in the large-scale swine farming system.