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The antitumor and antioxidative activities of polysaccharides isolated from Isaria farinosa B05

文献类型： 外文期刊

作者： Jiang, Yan-hua 1 ; Jiang, Xiao-lu 1 ; Wang, Peng 1 ; Mou, Hai-jin 1 ; Hu, Xiao-ke 1 ; Liu, Shu-qing 1 ;

作者机构： 1.Ocean Univ China, Inst Food Sci & Engn, Div Life Sci & Technol, Qingdao 266003, Peoples R China

2.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao 266071, Peoples R China

关键词： Isaria farinosa;polysaccharides;characteristic;antitumor;antioxidation

期刊名称：MICROBIOLOGICAL RESEARCH （ 影响因子：5.415； 五年影响因子：6.038 ）

ISSN： 0944-5013

年卷期： 2008 年 163 卷 4 期

页码：

收录情况： SCI

摘要： The water-soluble intra-polysaccharides WIPS1 and water-soluble extra-polysaccharides WEPS1 were isolated from Isaria farinosa B05 through ethanol precipitation and get permeation chromatography (GPC). Their characteristics were determined by chemical analysis, gas chromatography, GPC and IR spectroscopy. The results show that WIPS1 contained 90.3% carbohydrate, 8.00% uronic acid, 7.15% protein and three kinds of monosaccharides including mannose, galactose and glucose with a molar ratio of 8.0:4.8:1.0. WEPS1 contained 93.4% carbohydrate, 8.06% uronic acid, 4.40% protein and three kinds of monosaccharides including mannose, galactose and glucose with a molar ratio of 21.6:4.7: 1.0. WIPS1 and WEPS1 had a molecular weight of 42 and 208 kDa, respectively. The in vivo tests in mice indicate that WIPS1 and WEPS1 had significant antitumor and antioxidative activities to some extent. (c) 2006 Elsevier GrnbH. All rights reserved.

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