Isolation and Characterization of Seneca Valley Virus From Pig Transboundary Spread to the Mink Infection
文献类型： 外文期刊
作者： Qin, Ziliang 1 ; He, Xinmiao 2 ; Chen, Chao 1 ; Chen, Shaojun 1 ; Nai, Zida 1 ; Wang, Yao 3 ; Wang, Wentao 2 ; Li, Gang 1 ; Wang, Fang 2 ; Tian, Ming 2 ; He, Haijuan 2 ; Chen, Heshu 2 ; Liu, Di 1 ; Jiang, Xinpeng 1 ;
作者机构： 1.Northeast Agr Univ, Coll Anim Sci & Technol, Harbin, Heilongjiang, Peoples R China
2.Heilongjiang Acad Agr Sci, Inst Anim Husb, Harbin, Peoples R China
3.Peking Univ, Sch Life Sci, Beijing, Peoples R China
关键词： cross-host transmission; mink; Seneca Valley virus
期刊名称：TRANSBOUNDARY AND EMERGING DISEASES （ 影响因子：3.0； 五年影响因子：3.4 ）
ISSN： 1865-1674
年卷期： 2025 年 2025 卷 1 期
页码：
收录情况： SCI
摘要： Seneca Valley virus (SVV) infection has recently disseminated across pig farms in Canada, America, and China. The SVV has been identified in humans, rodents, and houseflies. Although cross-species transmission events may lead to limited subsequent transmission, sustained outbreaks have been observed in new mammalian hosts. Thus, in our study, we utilized molecular characteristics, pathological examination, and the immune response to ascertain whether mink could serve as a novel mammalian host for SVV. Here, our study utilized a porcine strain of SVV to infect minks orally, resulting in pathological changes in the intestines. In addition, SVV could stimulate a specific neutralizing antibody response. The neutralizing antibody against SVV has also been found in mink through an epidemiological investigation in Heilongjiang Province. This study highlights the role of SVV infection in minks as an impetus for viral evolution, which poses potential threats to livestock, public health, and economic prosperity.
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