The Dynamic Change of Gene-Regulated Networks in Cashmere Goat Skin with Seasonal Variation
文献类型： 外文期刊
作者： Hu, Sile 1 ; Li, Chun 2 ; Wu, Dubala 2 ; Huo, Hongyan 1 ; Bai, Haihua 1 ; Wu, Jianghong 3 ;
作者机构： 1.Inner Mongolia Univ Nationalities, Coll Life Sci & Food Engn, Tongliao 028000, Peoples R China
2.Inner Mongolia Univ Nationalities, Key Lab Bioinformat, Tongliao 028000, Peoples R China
3.Inner Mongolia Univ Nationalities, Coll Anim Sci & Technol, Tongliao 028000, Peoples R China
4.Inner Mongolia Acad Agr & Anim Husb Sci, Hohhot 010031, Peoples R China
5.Inner Mongolia Engn & Tech Res Ctr Personalized M, Tongliao 028000, Peoples R China
6.Inner Mongolia Univ Nationalities, Coll Life Sci & Food Engn, Inst Resource Biol & Ecol, Tongliao 028000, Peoples R China
关键词： Skin cycling; Cashmere goat; Transcriptome; Cutaneous immune system
期刊名称：BIOCHEMICAL GENETICS （ 影响因子：1.89； 五年影响因子：1.959 ）
ISSN： 0006-2928
年卷期：
页码：
收录情况： SCI
摘要： The Cashmere goat (Capra hircus) is renowned for its high-quality fiber production trait. The hair cycle in Cashmere goat has an annual rhythm. To deepen the understanding of the molecular foundation of annual rhythm in the skin of Cashmere goat, we did a comparative analysis of the Cashmere goat skin transcriptome all year round. 4002 Differentially expressed genes (DEGs) were identified with seasonal variations. 12 months transcriptome were divided into four developmental stages: Jan-Mar, Apr-Jul, Aug-Oct, and Nov-Dec based on gene expression patterns. 13 modules of highly correlated genes in skin were identified using WGCNA. Ten of these modules were consistent with the development stages. The gene function of those genes in each module was analyzed by functional enrichment. The results indicated that Wnt and Hedgehog signaling pathways were inhibited from January to March and activated from April to July. The cutaneous immune system of Cashmere goats has high activity from August to October. Fatty acid metabolism dominates goat skin from November to December. This study provides new information related to the annual skin development cycle, which could provide molecular biological significance for understanding the seasonal development and response to the annual rhythm of skin.
- 相关文献
作者其他论文 更多>>
-
Genomic adaptation to extreme climate conditions in beef cattle as a consequence of cross-breeding program
作者：Tian, Rugang;Nanaie, Hojjat Asadollahpour;Wang, Xiao;Dalai, Baolige;Zhao, Meng;Wang, Fenf;Li, Hui;Yang, Ding;Zhang, Hao;Li, Yuan;Wang, Tingyue;Nanaie, Hojjat Asadollahpour;Luan, Tu;Wu, Jianghong
关键词：Cattle; Cold adaptation; Whole-genome sequence; TRPM8
-
Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus
作者：Li, Chun;Feng, Cong;Ma, Guangyuan;Chen, Ming;Fu, Shaoyin;Chen, Ming;Zhang, Wenguang;Li, Jinquan
关键词：Hair follicle growth cycle; Cashmere goat; RNA-seq; Melatonin; Signaling pathway
-
The impact of different feeds on DNA methylation, glycolysis/gluconeogenesis signaling pathway, and gene expression of sheep muscle
作者：Song, Feng;Akonyani, Zaccheaus Pazamilala;Li, Ying;Su, Deqiqige;Wu, Lantuya;Pang, Yue;Wu, Dubala;Li, Chun;Wu, Jianghong;Hu, Sile;Yang, Ding;Wu, Jianghong
关键词：cAMP pathway; DNA methylation; Glucose metabolism; Glycolysis/Gluconeogenesis; Whole-genome bisulfite sequencing
-
Unraveling the Genetic Population Structure of Mongolian Indigenous Cattle Breeds Using Whole Genome Sequencing Data
作者：Tian, Rugang;Li, Yuan;Wang, Xiao;Zhao, Meng;Li, Hui;Zhang, Hao;Nanaie, Hojjat Asadollahpour;Wu, Jianghong
关键词：Mongolian cattle; Whole-genome; Population structure; Linkage disequilibrium
-
Effects of exogenous melatonin on expressional differences of immune-related genes in cashmere goats
作者：Chai, Yuan;Chai, Yuan;Liu, Zaixia;Guo, Lili;Dai, Lingli;Zhang, Wenguang;Liu, Zaixia;Fu, Shaoyin;Fu, Shaoyin;Liu, Bin;Sun, Yanyong;Zhang, Wenguang;Li, Chun;Liu, Taodi
关键词：cashmere goat; immune genes; melatonin; wool growth; high sulfur protein genes
-
Multiple omics analysis reveals that high fiber diets promote gluconeogenesis and inhibit glycolysis in muscle
作者：Wu, Jianghong;Wu, Jianghong;Yang, Ding;Qi, Yunxia;Sun, Hailian;Liu, Yongbin;Liu, Yahong;Qiu, Xiao;Gong, Husile
关键词：Glucose metabolism; Integrative analysis; Meat quality; Metabolome; Ruminal microbiome; Transcriptome
-
Evolution and Expression of S100A7 Gene in Vertebrates
作者：Gong, Husile;Wu, Jianghong;Yang, Ding;Qi, Yunxia;Wu, Jianghong;Gong, Husile;Zhang, Wenguang
关键词：
