文献类型： 外文期刊

作者： Lei, Qin ¹ ; Yin-Geng, Wang ² ; Zheng, Zhang ² ; Shao-Li, Yang ² ;

作者机构： 1.Chinese Acad Fishery Sci, Yellow Sea Fishery Res Inst, Qingdao 266071, Peoples R China

2.Chinese Acad Fishery Sci, Yellow Sea Fishery Res Inst, Qingdao 266071, Peoples R China; Ocean Univ China, Dept Life Sci, Qingdao 266003, Peoples R China

期刊名称：JOURNAL OF AQUATIC ANIMAL HEALTH （ 影响因子：1.625； 五年影响因子：1.786 ）

ISSN： 0899-7659

年卷期： 2006 年 18 卷 2 期

页码：

收录情况： SCI

摘要： Since 1998, the culture of turbot Scophthalmus maximus has spread rapidly along the coast of North China, becoming an important industry. However, fin rot disease was identified during an epidemiological study from 2001 to 2004. The infections occurred with high mortality, up to 90-100% in some cases. Young fish are sensitive to the infection. An important clinical sign is fin rot. Bacterial isolation was done in four cases, including hatcheries and farms. One dominant strain of 0.2-0.4 X 1.5-2.0 mu m was identified as Vibrio anguillarum by morphology, physiological and biochemical tests, and 16S rRNA sequence analysis. Virulence assays carried out with the isolated V. anguillarum resulted in the same gross signs as in naturally infected fish, indicating that V. anguillarum was the causative agent for fin rot disease. The 14-d dose lethal to 50% of the fish was calculated as 1.7 X 10(3) colony-forming units/mL. Histopathological studies demonstrated that V. anguillarum could cause severe tissue changes in most organs, such as the fin, skin, gills, kidney, spleen, liver, intestine, and brain. This is the first detailed report on fin rot disease of cultured turbot in China.