Residual Risk of Avermectins in Food Products of Animal Origin and Their Research Progress on Toxicity and Determination
文献类型： 外文期刊
作者： Qiao, Lu 1 ; Xu, Jinhua 1 ; Yang, Zhen 1 ; Li, Xingyang 1 ; Chen, Lu 1 ; Sun, Huiwu 1 ; Mu, Yingchun 1 ;
作者机构： 1.Chinese Acad Fishery Sci, Key Lab Control Qual & Safety Aquat Prod, Minist Agr & Rural Affairs, Beijing 100141, Peoples R China
2.Bohai Univ, Coll Food Sci & Engn, Jinzhou, Peoples R China
关键词： Avermectins; residue limits; toxicity; analytical methods; food products of animal origin
期刊名称：FOOD REVIEWS INTERNATIONAL （ 影响因子：6.043； 五年影响因子：6.79 ）
ISSN： 8755-9129
年卷期：
页码：
收录情况： SCI
摘要： Avermectins (AVMs) are categorised as highly effective but toxic natural products isolated from Streptomyces avermitilis and are widely applied as antihelminthic and antiparasitic agents in agriculture and aquaculture. AVMs accumulated in the environment through runoff, spray drift, field drainage, or from pharmaceutical drugs used for aquatic farming, which resulted in toxic effects on nontarget aquatic and terrestrial organisms and caused residues in food products of animal origin. There was a lack of comprehensive overview for residual risk of AVMs in food products of animal origin and their research progress on toxicity and determination. This paper introduced the structure and chemical properties of AVMs, then updated and classified residue limits of AVMs in food products of animal origin established by Codex Alimentarius Commission (CAC), European Union (EU), United States, Japan, and China. The toxicity of AVMs and analytical methods of AVMs in food products of animal origin were summarized. Besides, the residues of AVMs in food products of animal origin were analyzed. Further researches for impacts of AVMs on environment and potential toxicological significance of food contamination by AVMs are needed to understand their risk in the environment and food chain.
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