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Two new dihydro-beta-agarofuran sesquiterpenes from the roots of Celastrus angulatus

文献类型: 外文期刊

作者: Tang, Juan 1 ; Hu, Jia-Zhen 1 ; Chen, Yan-Ling 1 ; Zhao, Ting-Ting 1 ; Chen, Tao-Xiang 1 ; Hu, Cheng-Gang 1 ;

作者机构: 1.Guizhou Univ Tradit Chinese Med, Sch Pharm, Guiyang 550025, Peoples R China

2.Guizhou Acad Agr Sci, Guizhou Inst Prataculture, Guiyang 550025, Peoples R China

关键词: Celastraceae; Celastrus angulatus; dihydro-beta-agarofuran sesquiterpenes; single-crystal X-ray diffraction

期刊名称:JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH ( 影响因子:1.61; 五年影响因子:1.591 )

ISSN: 1028-6020

年卷期:

页码:

收录情况: SCI

摘要: Two new dihydro-beta-agarofuran sesquiterpenes chiapen T (1) and chiapen U (2), along with chiapen A (3), 1 beta-hydroxy-2 beta,6 alpha,12-triacetoxy-8 beta-(beta-nicotinoyloxy)-9 beta-(benzoyloxy)-beta-dihydroagarofuran (4), wilforlide B (5), 3-hydroxy-2-oxo-3-friedelen-29-oic acid (6), epikatonic acid (7), 22-epi-maytenfolic acid (8), maytenoic acid (9), wilforic acid F (10), wilforic acid B (11), were reported for the first time from the Celastrus angulatus. The structures of all the compounds were elucidated by HR-ESI-MS, 1 D and 2 D NMR spectra, as well as single-crystal X-ray diffraction analyses. Compounds 1 and 2 were examined for anti-inflammatory activity, respectively. None of them showed potent activity. [GRAPHICS] .

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