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Recent Advances on Antimicrobial Peptides from Milk: Molecular Properties, Mechanisms, and Applications

文献类型： 外文期刊

作者： Wang, Zhicheng 1 ; Xu, Jue 1 ; Zeng, Xiaoqun 1 ; Du, Qiwei 1 ; Lan, Hangzhen 1 ; Zhang, Jianming 3 ; Pan, Daodong 1 ; Tu, Maolin 1 ;

作者机构： 1.Ningbo Univ, State Key Lab Managing Biot & Chem Threats Qual &, Ningbo 315211, Zhejiang, Peoples R China

2.Ningbo Univ, Coll Food & Pharmaceut Sci, Zhejiang Malaysia Joint Res Lab Agr Prod Proc & Nu, Key Lab Anim Prot Food Deep Proc Technol Zhejiang, Ningbo 315800, Peoples R China

3.Zhejiang Acad Agr Sci, Inst Food Sci, Hangzhou 310016, Zhejiang, Peoples R China

关键词： milk protein; antimicrobial peptide; molecularproperty; activity mechanism; analytical technology; application

期刊名称：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY （ 影响因子：6.1； 五年影响因子：6.3 ）

ISSN： 0021-8561

年卷期： 2023 年 72 卷 1 期

页码：

收录情况： SCI

摘要： Traditional antibiotics are facing a tremendous challenge due to increased antimicrobial resistance; hence, there is an urgent need to find novel antibiotic alternatives. Milk protein-derived antimicrobial peptides (AMPs) are currently attracting substantial attention considering that they showcase an extensive spectrum of antimicrobial activities, with slower development of antimicrobial resistance and safety of raw materials. This review summarizes the molecular properties, and activity mechanisms and highlights the applications and limitations of AMPs derived from milk proteins comprehensively. Also the analytical technologies, especially bioinformatics methodologies, applied in the process of screening, identification, and mechanism illustration of AMPs were underlined. This review will give some ideas for further research and broadening of the applications of milk protein-derived AMPs in the food field.

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