文献类型： 外文期刊

作者： An Xuehua ¹ ; Lui Xinju ¹ ; Jiang Jinhua ¹ ; Wang Feidi ¹ ; Lv Lu ¹ ; Li Gang ¹ ; Wu Shenggan ¹ ; Zhao Xueping ¹ ;

作者机构： 1.Zhejiang Acad Agr Sci, Inst Agroprod Safety & Nutr, Hangzhou 310021, Zhejiang, Peoples R China

关键词： Prothioconazole; Prothioconazole-desthio; Daphnia magna; Acute toxicity; Chronic toxicity

期刊名称：ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH （ 影响因子：5.19； 五年影响因子：5.053 ）

ISSN： 0944-1344

年卷期： 2022 年 29 卷 36 期

页码：

收录情况： SCI

摘要： Current research on prothioconazole (PTC), a broad-spectrum triazole fungicide, mainly focuses on its efficacy and residues; only a few studies have been assessing its toxicological effects. Using acute and chronic toxicity tests, we assessed the effects of PTC and its metabolite prothioconazole-desthio (PTCd) on the inhibition of the activity, growth, and reproduction of Daphnia magna. A dose-response relationship was established to determine sensitive biological indicators. In the acute and chronic toxicity tests, the 48-h EC50 (concentration for 50% of the maximal effect) of PTC and PTCd for D. magna were 2.82 and 5.19 mg/L and 0.0807 and 0.132 mg/L, respectively; in the latter test, PTC was 1.64 times more toxic than PTCd. Acute-to-chronic toxicity ratios were calculated using chronic toxicity data; the ratios were 227 and 27.5 for PTC and PTCd, respectively. Our results indicate that both PTC and PTCd affect the growth and reproduction of D. magna and that the toxicity of PTC is greater than that of PTCd. In conclusion, the metabolites of PTD are toxic to D. magna at certain concentrations, and their environmental risks should not be neglected.