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Two new compounds isolated from the entomogenous fungus Fusarium sp. LGWB-7

文献类型: 外文期刊

作者: Liu, Sha Sha 1 ; Li, Chun Qing 1 ; Kong, Fan Dong 2 ; Ma, Qing Yun 2 ; Xie, Qing Yi 3 ; Zhou, Li Man 2 ; Luo, Du Qiang 1 ;

作者机构: 1.Hebei Univ, Inst Life Sci & Green Dev, Sch Life Sci, Baoding 071002, Peoples R China

2.CATAS, Haikou Key Lab Res & Utilizat Trop Nat Prod, Inst Trop Biosci & Biotechnol, Haikou 571101, Hainan, Peoples R China

3.CATAS, Hainan Acad Trop Agr Resource, Haikou 571101, Hainan, Peoples R China

关键词: Fusariumsp.; Entomogenous fungus; Metabolites; Cytotoxic activity

期刊名称:PHYTOCHEMISTRY LETTERS ( 影响因子:1.679; 五年影响因子:1.861 )

ISSN: 1874-3900

年卷期: 2021 年 41 卷

页码:

收录情况: SCI

摘要: Two new compounds, named fusariumtrin A (1) and climacomontaninate D (2), together with eight known ones were isolated from the rice culture of the Fusarium sp. LGWB-7, an entomogenous fungus isolated from the Harmonia axyridis. The structures of the new compounds were elucidated by the analysis of 1D and 2D spectroscopic data as well as mass spectrum (MS). Compound 10 showed cytotoxicity against K562, A549, SGC-7901, and Hela human tumor cell lines with IC50 values of 1.46, 13.97, 9.34, and 6.64 mu M, respectively.

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