您好，欢迎访问内蒙古农牧业科学院 机构知识库！
内蒙古农牧业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Regulatory pathway analysis of coat color genes in Mongolian horses

文献类型： 外文期刊

作者： Li, Bei 1 ; He, Xiaolong 2 ; Zhao, Yiping 1 ; Bai, Dongyi 1 ; Shiraigo, Wunierfu 1 ; Zhao, Qinan 1 ; Manglai, Dugarjav 1 ;

作者机构： 1.Inner Mongolia Agr Univ, Coll Anim Sci, Hohhot 010018, Peoples R China

2.Inner Mongolia Acad Agr & Anim Husb Sci, Hohhot 010031, Peoples R China

关键词： Mongolian horse;RNA-Seq;Coat color;Pigmentation;Tyrosine

期刊名称：HEREDITAS （ 影响因子：3.271； 五年影响因子：2.807 ）

ISSN： 1601-5223

年卷期： 2017 年 155 卷

页码：

收录情况： SCI

摘要： Background: Studies on the molecular genetics of horse skin pigmentation have typically focused on very few genes and proteins. In this study, we used Illumina sequencing to determine the global gene expression profiles in horses with white-colored coats and those with black-colored coats, with the goal of identifying novel genes that could regulate horse coat color. Results: Genes encoding ribosomal-associated proteins were highly expressed in horse skin. We found a total of 231 unigenes that were differentially expressed between horses with white coats and horses with black coats; 119 were down-regulated, and 112 were up-regulated. Many of the up-regulated genes in black horses, such as genes related to tyrosine metabolism, may directly regulate dark coat color. Keratin genes, MIA family genes, fatty acid-related genes, and melanoma-associated genes were also differentially regulated, which suggests that they may play important roles in coat color formation. Conclusions: These findings show that the transcription profiles from white and black horse skin provide useful information to understand the genetics underlying the control of skin melanin synthesis in horses, which may enhance our knowledge of human skin diseases, such as melanoma and albinism.

  • 相关文献

[1]Tyrosinase-related protein 1 (TYRP1) gene polymorphism and skin differential expression related to coat color in Mongolian horse. Li, Bei,Zhao, Yi-ping,Zhao, Qi-nan,Unierhu,Bai, Dong-yi,Manglai, Dugarjaviin,He, Xiao-long.

[2]基于RNA-Seq技术的盐胁迫向日葵转录组信息分析. 孙瑞芬,张艳芳,郭树春,于海峰,李素萍,聂惠,乔慧蕾,安玉麟. 2015

[3]基于RNA-Seq技术挖掘绵羊背最长肌肉质性状相关基因. 王位,付绍印,何小龙,王艳欣,王月星,王标,刘斌,刘永斌,张文广. 2018

[4]转录组研究新技术:RNA-Seq及其应用. 祁云霞,刘永斌,荣威恒. 2011

[5]基于RNA-Seq技术的向日葵油酸形成的转录组学分析. 于海峰,韩平安,李美娜,陈阜,郭树春,李素萍,张艳芳,赵建军,闫明霞. 2018

[6]纳米硒对甜菜叶片转录组的影响. 郑文哲,王莹莹,张辉,张必周,孙梦媛,王良,张惠忠,李晓东,付增娟,赵尚敏,鄂圆圆,张自强. 2024

[7]基于RNA-Seq的向日葵脂肪酸合成基因筛选与分析. 郭树春,张艳芳,李素萍,邵盈,邢慧军,于海峰. 2023

[8]RNA-Seq of Agropyron mongolicum Keng in response to drought stress. Ma, Yanhong,Yu, Xiaoxia,Yu, Zhuo,Li, XiaoLei,Sun, Fengcheng,Li, Xiaodong. 2018

[9]Large-scale transcriptome comparison of sunflower genes responsive to Verticillium dahliae. Guo, Shuchun,Zuo, Yongchun,Wu, Chengyan,Su, Wenxia,Jin, Wen,Li, Qianzhong,Guo, Shuchun,Zhang, Yanfang,Yu, Haifeng,An, Yulin,Zuo, Yongchun. 2017

作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：内蒙古农牧业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台