Gene expression profile changes in the jejunum of weaned piglets after oral administration of Lactobacillus or an antibiotic
文献类型： 外文期刊
作者： Zhang, Dongyan 1 ; Shang, Tingting 1 ; Huang, Yan 3 ; Wang, Sixin 2 ; Liu, Hui 2 ; Wang, Jing 2 ; Wang, Yamin 2 ; Ji, Hai 1 ;
作者机构： 1.China Agr Univ, Coll Anim Sci & Technol, State Key Lab Anim Nutr, Lab Feed Biotechnol, Beijing 100083, Peoples R China
2.Beijing Acad Agr & Forestry Sci, Inst Anim Husb & Vet Med, Beijing 100097, Peoples R China
3.China Agr Univ, Coll Informat & Elect Engn, Beijing 100083, Peoples R China
期刊名称：SCIENTIFIC REPORTS （ 影响因子：4.379； 五年影响因子：5.133 ）
ISSN： 2045-2322
年卷期： 2017 年 7 卷
页码：
收录情况： SCI
摘要： The small intestine plays an essential role in the health and well-being of animals. Previous studies have shown that Lactobacillus has a protective effect on intestinal morphology, intestinal epithelium integrity and appropriate maturation of gut-associated tissues. Here, gene expression in jejunum tissue of weaned piglets was investigated by RNA-seq analysis after administration of sterile saline, Lactobacillus reuteri, or an antibiotic (chlortetracycline). In total, 401 and 293 genes were significantly regulated by chlortetracycline and L. reuteri, respectively, compared with control treatment. Notably, the HP, NOX1 and GPX2 genes were significantly up-regulated in the L. reuteri group compared with control, which is related to the antioxidant ability of this strain. In addition, the expression of genes related to arachidonic acid metabolism and linoleic acid metabolism enriched after treatment with L. reuteri. The fatty acid composition in the jejunum and colon was examined by GC-MS analysis and suggested that the MUFA C18:1n9c, and PUFAs C18:2n6c and C20:4n6 were increased in the L. reuteri group, verifying the GO enrichment and KEGG pathway analyses of the RNA-seq results. The results contribute to our understanding of the probiotic activity of this strain and its application in pig production.
- 相关文献
作者其他论文 更多>>
-
Altering Carotene Hydroxylase Activity of DcCYP97C1 Affects Carotenoid Flux and Changes Taproot Colour in Carrot
作者：Deng, Yuan-Jie;Duan, Ao-Qi;Li, Tong;Tan, Shan-Shan;Liu, Shan-Shan;Wang, Ya-Hui;Ma, Jing;Li, Jing-Wen;Liu, Hui;Xu, Zhi-Sheng;Xiong, Ai-Sheng;Liang, Yi;Zhou, Jian-Hua
关键词：carotene hydroxylase; carotenoid; carrot; CRISPR/Cas9
-
High-throughput phenotyping techniques for forage: Status, bottleneck, and challenges
作者：Cheng, Tao;Zhang, Dongyan;Cheng, Tao;Wang, Zhaoming;Zhang, Dongyan;Zhang, Gan;Yuan, Feng;Liu, Yaling;Wang, Tianyi;Ren, Weibo;Zhao, Chunjiang
关键词：Forage; High-throughput phenotyping; Precision identification; Sensors; Artificial intelligence; Efficient breeding
-
Carotene hydroxylase DcCYP97A3 affects carotenoid metabolic flow and taproot color by influencing the conversion of α-carotene to lutein in carrot
作者：Wang, Hui-Ru;Zhang, Rong-Rong;Wang, Ya-Hui;Sun, Miao;Wang, Li-Xiang;Zhang, Yu-Qing;Xu, Zhi-Sheng;Ma, Jing;Liu, Hui;Tao, Jian-Ping;Xiong, Ai-Sheng;Zhou, Jian-Hua;Sun, Miao;Liang, Yi;Li, Xiao-Jie
关键词：
-
EasyMetagenome: A user-friendly and flexible pipeline for shotgun metagenomic analysis in microbiome research
作者：Bai, Defeng;Xun, Jiani;Ma, Chuang;Luo, Hao;Yang, Haifei;Hou, Huiyu;Lv, Hujie;Wan, Xiulin;Wang, Yao;Yousuf, Salsabeel;Zeng, Meiyin;Zhang, Tianyuan;Gao, Yunyun;Liu, Yong-Xin;Chen, Tong;Ma, Chuang;Yang, Haifei;Cao, Chen;Cao, Xiaofeng;Cui, Jianzhou;Deng, Yuan-Ping;Deng, Zhaochao;Yu, Hao;Zhang, Chunfang;Dong, Wenxin;Dong, Wenxue;Du, Juan;Fang, Qunkai;Fang, Wei;Fang, Yue;Luan, Yaning;Fu, Fangtian;Fu, Min;Fu, Yi-Tian;Gao, He;Ge, Jingping;Guo, Yuhao;Gong, Qinglong;Lou, Wenbo;Gu, Lunda;Yang, Li;Guo, Peng;Hai, Tang;Liu, Hao;He, Jieqiang;He, Zi-Yang;Huang, Can;Ji, Shuai;Jiang, ChangHai;Jiang, Gui-Lai;Jiang, Lingjuan;Jin, Ling N.;Li, Changchao;Kan, Yuhe;Kang, Da;Kou, Jin;Lam, Ka-Lung;Li, Chong;Li, Fuyi;Li, Liwei;Li, Miao;Li, Xin;Li, Ye;Li, Zheng-Tao;Zhu, Chengshuai;Liang, Jing;Mo, Jiayuan;Lin, Yongxin;Liu, Changzhen;Liu, Danni;Zhang, Jing;Chen, Shifu;Liu, Fengqin;Liu, Jia;Liu, Tianrui;Liu, Tingting;Wang, Xinlong;Liu, Xinyuan;Luo, Yuanyuan;Liu, Yaqun;Liu, Bangyan;Liu, Minghao;Lv, Hujie;Ma, Tengfei;Mai, Zongjiong;Niu, Dongze;Pan, Zhuo;Qi, Heyuan;Shi, Zhanyao;Song, Chunjiao;Sun, Fuxiang;Sun, Yan;Tian, Sihui;Wang, Guoliang;Wang, Hongyang;Wang, Hongyu;Wang, Huanhuan;Wang, Jing;Wang, Jun;Wang, Kang;Wang, Leli;Yao, Xiaofang;Wang, Shao-kun;Xiao, Zufei;Xing, Huichun;Xu, Yifan;Yang, Song;Yan, Shu-yan;Zhang, Yi-Bo;Yang, Yuanming;Lei, Yu;Yuan, Zhengrong;Zhang, Chunge;Zhang, Huimin;Zhang, Na;Zhang, Yupeng;Zhang, Zheng;Zhou, Mingda;Zhou, Yuanping;Zhu, Zhihao;Zhu, Lin;Zhu, Yue;Zou, Hongqin;Zuo, Anna;Dong, Wenxuan;Wen, Tao;Chen, Shifu;Chen, Shifu;Li, Guoliang
关键词：metagenome; microbiome; microbiota; pipeline; visualization
-
Calycosin, a Bioactive Isoflavone, Ameliorates Oxidative Stress and Inflammation in Lipopolysaccharide-Induced Intestinal Cell Damage Model via the Nrf2 and NF-κB Signaling Pathways
作者：Li, Lu;Che, Yuyan;Zhu, Longlong;Liu, Zeqing;Song, Yanchen;Chen, Meixia;Wang, Jing;Li, Lu;Che, Yuyan;Song, Yanchen;Zhu, Longlong;Liu, Zeqing;Wu, Qiong;Chen, Meixia;Wang, Jing
关键词：calycosin; cell damage; inflammation; LPS; NF-kappa B pathway; Nrf2 pathway; oxidative stress
-
Chromosome-level genome assembly of tetraploid Chinese cherry (Prunus pseudocerasus)
作者：Zhang, Wei;Wang, Xuncheng;Peng, Junbo;Xing, Qikai;Yan, Jiye;Wang, Jing;Duan, Xuwei;Zhang, Xiaoming;Zhang, Kaichun
关键词：
-
DcMADS3, a MADS-Box Transcription Factor, Highly Expressed at the Middle Flower Bud Stage and Involved in Petalization Development in Carrot
作者：Tan, Shan-Shan;Liu, Shan-Shan;Duan, Ao-Qi;Deng, Yuan-Jie;Wang, Ya-Hui;Liu, Hui;Xu, Zhi-Sheng;Xiong, Ai-Sheng;Ma, Jing;Liang, Yi
关键词：Carrot; Floral organ; MADS-box transcription factor; Overexpression; Interaction analysis
