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Synthesis, characterization, and biological activities of some transition metal(II) complexes with the thiosemicarbazone derived from 4-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]but-3-en-2-one

文献类型: 外文期刊

作者: Qu, J. Q. 1 ; Sun, G. C. 2 ; Wang, L. F. 2 ; Qu, L. 2 ;

作者机构: 1.Tianjin Univ, Sch Sci, Dept Chem, Tianjin 300072, Peoples R China

2.Tianjin Univ, Sch Sci, Dept Chem, Tianjin 300072, Peoples R China; Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China; Ningxia Acad Agr & Forestry Sci, Yinchuan 750002, Peoples R China

期刊名称:CHEMICAL PAPERS-CHEMICKE ZVESTI ( 影响因子:0.963; 五年影响因子:1.198 )

ISSN: 0366-6352

年卷期: 2006 年 60 卷 3 期

页码:

收录情况: SCI

摘要: A new 4-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]but-3-en-2-one thiosemicarbazone (HL) was synthesized derived from 4-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]but-3-en-2-one. Four transition metal(II) complexes of HL have been prepared. Elemental analysis, molar conductivity, IR, UV, H-1 NMR spectra, and TG-DTA have been used to characterize these complexes. The complexes have the general formula ML2, where M = Zn, Cu, Co, and Ni. The ligand and its complexes have been studied for their possible biological activity including anti-inflammatory, antibacterial, and antitumour activity in vitro.

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