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Comparative mitochondrial genomics toward exploring molecular markers in the medicinal fungus Cordyceps militaris

文献类型: 外文期刊

作者: Zhang, Shu 1 ; Hao, Ai-Jing 2 ; Zhao, Yu-Xiang 2 ; Zhang, Xiao-Yu 3 ; Zhang, Yong-Jie 2 ;

作者机构: 1.Shanxi Univ, Inst Appl Chem, Taiyuan 030006, Peoples R China

2.Shanxi Univ, Sch Life Sci, Taiyuan 030006, Shanxi, Peoples R China

3.Shanxi Acad Agr Sci, Farm Prod Storage & Freshening Inst, Taiyuan 030031, Shanxi, Peoples R China

期刊名称:SCIENTIFIC REPORTS ( 影响因子:4.379; 五年影响因子:5.133 )

ISSN: 2045-2322

年卷期: 2017 年 7 卷

页码:

收录情况: SCI

摘要: Cordyceps militaris is a fungus used for developing health food, but knowledge about its intraspecific differentiation is limited due to lack of efficient markers. Herein, we assembled the mitochondrial genomes of eight C. militaris strains and performed a comparative mitochondrial genomic analysis together with three previously reported mitochondrial genomes of the fungus. Sizes of the 11 mitochondrial genomes varied from 26.5 to 33.9 kb mainly due to variable intron contents (from two to eight introns per strain). Nucleotide variability varied according to different regions with non-coding regions showing higher variation frequency than coding regions. Recombination events were identified between some locus pairs but seemed not to contribute greatly to genetic variations of the fungus. Based on nucleotide diversity fluctuations across the alignment of all mitochondrial genomes, molecular markers with the potential to be used for future typing studies were determined.

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