RNA-Seq Analyses for Two Silkworm Strains Reveals Insight into Their Susceptibility and Resistance to Beauveria bassiana Infection
文献类型: 外文期刊
作者: Xing, Dongxu 1 ; Yang, Qiong 2 ; Jiang, Liang 1 ; Li, Qingrong 2 ; Xiao, Yang 2 ; Ye, Mingqiang 2 ; Xia, Qingyou 1 ;
作者机构: 1.Southwest Univ, State Key Lab Silkworm Genome Biol, Chongqing 400715, Peoples R China
2.Guangdong Acad Agr Sci, Sericulture & Agri Food Res Inst, Guangzhou 510610, Guangdong, Peoples R China
关键词: silkworm;RNA-seq;Beauveria bassiana;resistance
期刊名称:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ( 影响因子:5.923; 五年影响因子:6.132 )
ISSN: 1422-0067
年卷期: 2017 年 18 卷 2 期
页码:
收录情况: SCI
摘要: The silkworm Bombyx mori is an economically important species. White muscardine caused by Beauveria bassiana is the main fungal disease in sericulture, and understanding the silkworm responses to B. bassiana infection is of particular interest. Herein, we investigated the molecular mechanisms underlying these responses in two silkworm strains Haoyue (HY, sensitive to B. bassiana) and Kang 8 (K8, resistant to B. bassiana) using an RNA-seq approach. For each strain, three biological replicates for immersion treatment, two replicates for injection treatment and three untreated controls were collected to generate 16 libraries for sequencing. Differentially expressed genes (DEGs) between treated samples and untreated controls, and between the two silkworm strains, were identified. DEGs and the enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of the two strains exhibited an obvious difference. Several genes encoding cuticle proteins, serine proteinase inhibitors (SPI) and antimicrobial peptides (AMP) and the drug metabolism pathway involved in toxin detoxification were considered to be related to the resistance of K8 to B. bassiana. These results revealed insight into the resistance and susceptibility of two silkworm strains against B. bassiana infection and provided a roadmap for silkworm molecular breeding to enhance its resistance to B. bassiana.
- 相关文献
作者其他论文 更多>>
-
Targeted and non-targeted metabolic characteristics of 6,7-dihydroxy-2,4-dimethoxyphenanthrene during simulated gastrointestinal digestion
作者:Li, Qian;Liu, Fan;Liao, Sentai;Zhou, Donglai;Xing, Dongxu;Zou, Yuxiao
关键词:Phenanthrenes; Chinese yam; Gastrointestinal digestion; Characteristic metabolism
-
Dietary supplementation of mulberry leaf oligosaccharides improves the growth, glucose and lipid metabolism, immunity, and virus resistance in largemouth bass (Micropterus salmoides)
作者:Zhou, Donglai;Zhong, Wenhao;Fu, Bing;Li, Erna;Li, Qingrong;Yang, Qiong;Zou, Yuxiao;Liao, Sentai;Xing, Dongxu;Zhou, Donglai;Li, Erna;Wang, Fubao;Zhong, Wenhao;Hao, Le;Liu, Zhenxing
关键词:largemouth bass; growth; serum biochemistry; liver metabolism; inflammation
-
Mulberry leaf extract reduces damage by regulating the oxidative response, immune response and intestinal flora of largemouth bass (Micropterus salmoides) under chronic heat stress
作者:Fu, Bing;Zhou, Donglai;Qiu, Xiaotong;Zheng, Jieqiu;Yang, Qiong;Xiao, Yang;Liao, Sentai;Li, Qingrong;Xing, Dongxu;Qiu, Xiaotong;Zheng, Jieqiu
关键词:mulberry leaf extract; largemouth bass; heat stress; intestinal flora; liver injury; immune ability
-
Hsp70-mediated manipulation of antimicrobial peptide-related genes promotes BmNPV proliferation in Bombyx mori at relatively high temperatures
作者:Zhang, Jie;Hu, Yingying;Feng, Jiawei;He, Na;Li, Xiaofeng;Liyi, Qingge;Yi, Huiyu;Yang, Wanying;Zhang, Jie;Yang, Qiong
关键词:Bombyx mori; BmNPV; Innate immunity; Host-pathogen interaction; Heat shock protein (Hsp); Antimicrobial peptide (AMP)
-
Anti-Hyperuricemic and Nephroprotective Effects of Hydrolysate Derived from Silkworm Pupae (Bombyx mori): In Vitro and In Vivo Study
作者:Fan, Yuting;Yang, Zhencong;Lin, Xiao;Xu, Zhoujin;Wu, Xuli;Mu, Lixia;Li, Qingrong
关键词:silkworm pupae; peptides; anti-hyperuricemic; anti-inflammatory; xanthine oxidase
-
Combined modified atmosphere package and melatonin treatments delay the senescence of bitter bamboo shoots by inhibiting the cell wall changes after harvest
作者:Wang, Ling;Zhang, Shuo;Luo, Zheng;Chen, Yulong;Qi, Yingwei;Ye, Mingqiang;Chen, Feiping;Dai, Fanwei;Huang, Hua
关键词:Bitter bamboo shoot; Postharvest shelf-life; Modified atmosphere package; Melatonin; Lignin; Cell wall polysaccharides
-
Comparative study of intelligent sensory technologies combined multiple metabolomics in evaluating sensory attributes and health profiles across different grades and varieties of green tea-processed mulberry leaf tea
作者:Lin, Junhui;Yang, Zhangchang;Li, Qian;Wang, Weifei;Liao, Sentai;Xing, Dongxu;Pang, Daorui;Zou, Yuxiao;Chen, Ruohong
关键词:Mulberry leaf tea; After frost; Different grades; Volatile metabolites; Nonvolatile metabolites; Bioactive substances; Lignans; Intelligent sensory technologies



