您好，欢迎访问广东省农业科学院 机构知识库！
广东省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

The multi-herbal formula Chong-Myung-Tang improves spatial memory and increases cell genesis in the dentate gyrus of aged mice

文献类型： 外文期刊

作者： Liu, Lei 1 ; Zhang, Mingwei 1 ; Zhang, Ruifen 1 ; Lee, Mira 2 ; Wang, Zhen 3 ; Hou, Jingang 2 ; Sung, Chang-Keun 2 ;

作者机构： 1.Guangdong Acad Agr Sci, Key Lab Funct Food, Minist Agr, Sericultural & Agri Food Res Inst, Guangzhou, Guangdong, Peoples R China

2.Chungnam Natl Univ, Coll Agr & Biotechnol, Dept Food Sci & Technol, Taejon, South Korea

3.Linyi Univ, Modern Tradit Chinese Med Inst, Linyi, Peoples R China

关键词： dentate gyrus;cell proliferation;cell survival;spatial memory;Chong-Myung-Tang

期刊名称：BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY （ 影响因子：2.043； 五年影响因子：2.017 ）

ISSN： 0916-8451

年卷期： 2014 年 78 卷 10 期

页码：

收录情况： SCI

摘要： Chong-Myung-Tang (CMT) is a multi-herbal formula that has been used to improve memory. However, the potential mechanism remains unknown. The present study investigated the effects of CMT (50, 100, and 200 mg/kg) on spatial memory of aged mice. The behavioral training tests indicated that 200 mg/kg CMT treatment can significantly improve spatial memory of aged mice in the Morris water maze. Moreover, cell survival was examined by injecting bromodeoxyuridine (BrdU) on the first three days. The result showed that 200 mg/kg CMT treatment significantly increased cell survival in the dentate gyrus. Cell proliferation was determined by injecting BrdU 2 h before the mice were killed. The result suggested that CMT treatments had no influence on cell proliferation in the dentate gyrus. Thus, an increase in cell survival in the dentate gyrus stimulated by CMT may be involved in the effect of CMT on spatial memory improvement.

  • 相关文献

[1]Heat stress inhibits proliferation, promotes growth, and induces apoptosis in cultured Lantang swine skeletal muscle satellite cells. Gao, Chun-qi,Zhao, Yin-ling,Sui, Wei-guo,Yan, Hui-chao,Wang, Xiu-qi,Li, Hai-chang. 2015

[2]MiR-34b-5p Suppresses Melanoma Differentiation-Associated Gene 5 (MDA5) Signaling Pathway to Promote Avian Leukosis Virus Subgroup J (ALV-J)-Infected Cells Proliferaction and ALV-J Replication. Li, Zhenhui,Luo, Qingbin,Xu, Haiping,Zheng, Ming,Abdalla, Bahareldin Ali,Feng, Min,Cai, Bolin,Zhang, Xiaocui,Nie, Qinghua,Zhang, Xiquan,Li, Zhenhui,Luo, Qingbin,Xu, Haiping,Zheng, Ming,Abdalla, Bahareldin Ali,Feng, Min,Cai, Bolin,Zhang, Xiaocui,Nie, Qinghua,Zhang, Xiquan,Li, Zhenhui,Luo, Qingbin,Xu, Haiping,Zheng, Ming,Abdalla, Bahareldin Ali,Feng, Min,Cai, Bolin,Zhang, Xiaocui,Nie, Qinghua,Zhang, Xiquan. 2017

[3]Circular RNAs are abundant and dynamically expressed during embryonic muscle development in chickens. Ouyang, Hongjia,Chen, Xiaolan,Wang, Zhijun,Yu, Jiao,Jia, Xinzheng,Li, Zhenhui,Luo, Wei,Abdalla, Bahareldin Ali,Jebessa, Endashaw,Nie, Qinghua,Zhang, Xiquan,Ouyang, Hongjia,Chen, Xiaolan,Wang, Zhijun,Yu, Jiao,Jia, Xinzheng,Li, Zhenhui,Luo, Wei,Abdalla, Bahareldin Ali,Jebessa, Endashaw,Nie, Qinghua,Zhang, Xiquan,Ouyang, Hongjia,Chen, Xiaolan,Wang, Zhijun,Yu, Jiao,Jia, Xinzheng,Li, Zhenhui,Luo, Wei,Abdalla, Bahareldin Ali,Jebessa, Endashaw,Nie, Qinghua,Zhang, Xiquan. 2018

[4]Effects of dietary glycyl-glutamine on growth performance, small intestinal integrity, and immune responses of weaning piglets challenged with lipopolysaccharide. Jiang, Z. Y.,Lin, Y. C.,Ma, X. Y.,Zheng, C. T.,Zhou, G. L.,Chen, F.,Zou, S. T.,Sun, L. H..

[5]CpG oligodeoxynucleotides augment the immune responses of piglets to swine Pasteurella multocida living vaccine in vivo. Zhang Linghua,Tian Xingshan,Zhou Fengzhen.

[6]Conjugated linoleic acid differentially regulates fat deposition in backfat and longissimus muscle of finishing pigs. Jiang, Z. Y.,Zhong, W. J.,Zheng, C. T.,Lin, Y. C.,Jiang, S. Q.,Zhong, W. J.,Yang, L..

[7]Effect of sodium butyrate on cell proliferation and cell cycle in porcine intestinal epithelial (IPEC-J2) cells. Qiu, Yueqin,Ma, Xianyong,Yang, Xuefen,Wang, Li,Jiang, Zongyong.

作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：广东省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台