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New Xanthone from the Pericarp of Garcinia mangostana

文献类型: 外文期刊

作者: Fu, Manqin 1 ; Qiu, Samuel X. 2 ; Xu, Yujuan 1 ; Wu, Jijun 1 ; Chen, Yulong 1 ; Yu, Yuanshan 1 ; Xiao, Gengsheng 1 ;

作者机构: 1.Guangdong Acad Agr Sci, Guangdong Open Access Lab Agrifood Proc, Sericulture & Agrifood Res Inst, Guangzhou 510610, Guangdong, Peoples R China

2.Chinese Acad Sci, South China Bot Garden, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou 510650, Guangdong, Peoples R China

关键词: Garcinia mangostana;Xanthone;Cytotoxicity

期刊名称:NATURAL PRODUCT COMMUNICATIONS ( 影响因子:0.986; 五年影响因子:1.068 )

ISSN: 1934-578X

年卷期: 2013 年 8 卷 12 期

页码:

收录情况: SCI

摘要: A new prenylxanthone, garcimangostanol (1), was isolated from the EtOAc-soluble partition of the ethanol extract of the pericarp of Garcinia mangostana L., along with three known compounds, namely 8-deoxygartanin (2), 1-isomangostin (3), and garcinone C (4). The structure of compound 1 was elucidated on the basis of its 1D, 2D NMR and MS data. Compounds 1-4 exhibited either significant or moderate cytotoxicity against MCF-7, A549, Hep-G2 and CNE human cancer cell lines in vitro with IC50 values from 4.0 +/- 0.3 to 23.6 +/- 1.5 mu M by MU colorimetric assay.

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