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Influences of Selenium on the Ducklings Hepatic Mitochondrial Respiratory Function Changes Induced by Aflatoxin B-1

文献类型: 外文期刊

作者: Shi, Dayou 1 ; Guo, Shining 1 ; Liao, Shenquan 2 ; Tang, Zhaoxin 1 ;

作者机构: 1.South China Agr Univ, Coll Vet Med, Guangzhou, Guangdong, Peoples R China

2.Guangdong Acad Agr Sci, Inst Vet Med, Guangzhou, Guangdong, Peoples R China

关键词: Aflatoxin B-1;Hepatic mitochondrial;Respiratory function;Ducklings;Sodium selenite

期刊名称:ISBE 2011: 2011 INTERNATIONAL CONFERENCE ON BIOMEDICINE AND ENGINEERING, VOL 3

ISSN:

年卷期: 2011 年

页码:

收录情况: SCI

摘要: In order to observe the influences of aflatoxin B-1 (AFB(1)) on hepatic mitochondrial respiratory function in ducklings and study the antagonistic effect of sodium selenite (Na2SeO3) on AFB(1). Seven day-old ducklings were used as experimental animals. All animals were divided into three groups (30 animals each). The ducklings of group I was fed on the same volume of DMSO only with the other group as control. Group II, III were administered intragastrically AFB(1) at a dose 0.1mg/kg body weight respectively, and group III was fed on sodium selenite at a dose 1mg/kg. All treatments were given once daily during 7-28 day-old. The ducklings hepatic mitochondrial respiratory function was detected on 7th, 14th, 21th day after treatment. The results showed that the hepatic mitochondrial respiratory function was decrescenced in AFB(1) treated ducklings (Group II, III) (P<0.05), and the hepatic mitochondrial respiratory function of sodium selenite treated group (group III) was higher than group II (P<0.05). These results revealed that sodium selenite could ameliorate the hepatic mitochondrial respiratory function changes induced by aflatoxin B-1.

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