文献类型： 外文期刊

作者： Chen, GY ¹ ; Lin, BR ² ; Lin, YC ² ; Xie, FC ² ; Lu, W ³ ; Fong, WF;

作者机构： 1.Zhongshan Univ, Dept Appl Chem, Guangzhou 510275, Peoples R China

2.Zhongshan Univ, Dept Appl Chem, Guangzhou 510275, Peoples R China; Hainan Normal Univ, Dept Chem, Haikou 571158, Peoples R China; Guangdong Acad Agr Sci, Inst Plant Protect, Guangzhou 510000, Peoples R China; City Univ Hong Kong, Dept Biol & Chem, Hong Kong, Hong Kong, Peoples R China

3.Zhongshan Univ, Dept Appl Chem, Guangzhou 510275, Peoples R China; Hainan Normal Univ, Dept Chem

关键词： Streptomyces sp.;antimycin;antimicrobial activity;fungicide;macrodiolide;actinomycete

期刊名称：JOURNAL OF ANTIBIOTICS （ 影响因子：2.649； 五年影响因子：2.772 ）

ISSN： 0021-8820

年卷期： 2005 年 58 卷 8 期

页码：

收录情况： SCI

摘要： Directed bioassay guided fraction led to a new macrodiolide antimycin A(17) (1), isolated from a Streptomyces sp. GAAS7310, which showed significant antimicrobial activity against eleven fungal species, including Curvularia lunata (Wakker) Boed, Rhizopus nigrtcans Ehrb and Colletotrichum nigrum EL. et Halst. The structure was unambiguously established by interpretation of ID and 2D NMR data and comparison with the known antimycin A(1a).