Genetic characterization of subtype H1 avian influenza viruses isolated from live poultry markets in Zhejiang Province, China, in 2011
文献类型: 外文期刊
作者: Wu, Hai-bo 1 ; Guo, Chao-tan 2 ; Lu, Ru-feng 3 ; Xu, Li-hua 4 ; Wo, En-kang 2 ; You, Jin-biao 2 ; Wang, Yi-ting 2 ; Wang, 1 ;
作者机构: 1.Zhejiang Univ, Sch Med, Affiliated Hosp 1, State Key Lab Diag & Treatment Infect Dis, Hangzhou 310003, Zhejiang, Peoples R China
2.Zhejiang Acad Med Sci, Inst Bioengn, Hangzhou 310013, Zhejiang, Peoples R China
3.Zhejiang Chinese Med Univ, Affiliated Hosp 1, Dept Emergency, Hangzhou 310006, Zhejiang, Peoples R China
4.Zhejiang Acad Agr Sci, Anim Husb & Vet Inst, Hangzhou 310021, Zhejiang, Peoples R China
关键词: Avian influenza viruses;Subtype H1;Genetic analysis;Domestic ducks;Re-assortment
期刊名称:VIRUS GENES ( 影响因子:2.332; 五年影响因子:2.0 )
ISSN: 0920-8569
年卷期: 2012 年 44 卷 3 期
页码:
收录情况: SCI
摘要: Nine avian influenza A viruses (AIVs), H1N2 (n = 2) and H1N3 (n = 7), were isolated from domestic ducks in live poultry markets in Zhejiang Province, Eastern China, in 2011. All viruses were characterized by whole genome sequencing with subsequent phylogenetic analysis and genetic comparison. Phylogenetic analysis of all eight viral genes showed that the viruses clustered in the Eurasian lineage of influenza A viruses. The hemagglutinin cleavage site of all viruses displayed features of a monobasic cleavage site. Although there was no evidence of re-assortment in subtype H1 AIVs among the avian species and mammalian hosts in this study, continued surveillance is needed considering the important role of the domestic duck in the dissemination and re-assortment of AIVs.
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