文献类型： 外文期刊
作者： Chen, Qiu 1 ; Yan, Chengqi 2 ; Yan, Qingfeng 1 ; Feng, Lifeng 1 ; Chen, Jianping 2 ; Qian, Kaixian 1 ;
作者机构： 1.Zhejiang Univ, Coll Life Sci, Hangzhou 310027, Peoples R China
2.Zhejiang Acad Agr Sci, Hangzhou, Peoples R China
3.Soochow Univ, Sch Radiol & Publ Hlth, Suzhou, Peoples R China
关键词： MGC13096;proliferation
期刊名称：CELL BIOCHEMISTRY AND FUNCTION （ 影响因子：3.685； 五年影响因子：3.133 ）
ISSN： 0263-6484
年卷期： 2008 年 26 卷 2 期
页码：
收录情况： SCI
摘要： We report a functional characterisation of the novel protein MGC 13096. MGC 13096 over-expression restrained proliferation of HEK293T cells. DNA/flow cytometry analysis showed that the over-expression of MGC 13096 severely delays cell cycle progression at S phase. Transcription factors such as activator protein-1 (AP-1), cAMP response element binding protein (CREB), nuclear factor of activated T cells (NFAT), NF-kappa B, signal transducer and activator of transcription 1 (STAT1) took part in the process. Copyright (c) 2007 John Wiley & Sons, Ltd.
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