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Rifamycin S and its geometric isomer produced by a newly found actinomycete, Micromonospora rifamycinica

文献类型： 外文期刊

作者： Huang, Huiqin 1 ; Wu, Xiaopeng 1 ; Yi, Sheng 2 ; Zhou, Zhiwang 2 ; Zhu, Jun 1 ; Fang, Zhe 1 ; Yue, Jianmin 2 ; Bao, Shixi 1 ;

作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Trop Crop Biotechnol, Minist Agr, Haikou, Peoples R China

2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China

关键词： Micromonospora rifamycinica;MRSA;Rifamycin;Geometric isomer;Spectroscopic analyze

期刊名称：ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY （ 影响因子：2.271； 五年影响因子：2.707 ）

ISSN： 0003-6072

年卷期： 2009 年 95 卷 2 期

页码：

收录情况： SCI

摘要： Strain AM105 was separated from mangrove sediment in the South China Sea in this research. The morphological and genomic data showed that the strain merits description as a novel species, proposed as Micromonospora rifamycinica. From the acetate ethyl extract of its fermentation broth, two antibiotics against Gram-positive bacteria (including MRSA), rifamycin S and its geometric isomer were isolated. Their structures were elucidated on the basis of spectroscopic analyzes. (1)H and (13)C NMR data of the isomer of rifamycin S were first described in this paper.

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