Chemical composition and in vitro evaluation of the cytotoxic and antioxidant activities of supercritical carbon dioxide extracts of pitaya (dragon fruit) peel
文献类型: 外文期刊
作者: Luo, Hui 1 ; Cai, Yongqiang 1 ; Peng, Zhijun 1 ; Liu, Tao 1 ; Yang, Shengjie 2 ;
作者机构: 1.Guizhou Acad Agr Sci, Guizhou Fruit Inst, Guiyang 550006, Peoples R China
2.Beijing Haiyan Pharmaceut Co Ltd, Yangtze River Pharmaceut Grp, Res Inst Tradit Chinese Med, Beijing 102206, Peoples R China
3.Guizhou Univ, Minist Educ, Key Lab Green Pesticide & Agr Bioengn, State key Lab Breeding Base Green Pesticide & Agr, Guiyang 550025, Peoples R China
期刊名称:CHEMISTRY CENTRAL JOURNAL ( 影响因子:4.215; 五年影响因子:3.836 )
ISSN: 1752-153X
年卷期: 2014 年 8 卷
页码:
收录情况: SCI
摘要: Background: Hylocereus polyrhizus and Hylocereus undatus are two varieties of the commonly called pitaya fruits, and pitaya fruits have gained popularity in many countries all over the world. However, studies on chemical composition and the nutritional quality of pitaya flesh peel are limited. Results: Extracts of pitaya (H. polyrhizus and H. undatus) peel were extracted by supercritical carbon dioxide extraction, and analyzed by gas chromatography-mass spectrometry analysis. Their cytotoxic and antioxidant activities were investigated. The main components of H. polyrhizus extract were beta-amyrin (15.87%), alpha-amyrin (13.90%), octacosane (12.2%), gamma-sitosterol (9.35%), octadecane (6.27%), 1-tetracosanol (5.19%), stigmast-4-en-3-one (4.65%), and campesterol (4.16%), whereas H. undatus were beta-amyrin (23.39%), gamma-sitosterol (19.32%), and octadecane (9.25%), heptacosane (5.52%), campesterol (5.27%), nonacosane (5.02%), and trichloroacetic acid, hexadecyl ester (5.21%). Both of the two extracts possessed good cytotoxic activities against PC3, Bcap-37, and MGC-803 cells (IC50 values ranging from 0.61 to 0.73 mg/mL), and the activities of their main components were also studied. Furthermore, these extracts also presented some radical scavenging activities, with IC50 values of 0.83 and 0.91 mg/mL, respectively. Conclusion: This paper provides evidence for studying the chemical composition of supercritical carbon dioxide extracts of pitaya peel and their biological activity.
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