文献类型： 外文期刊

作者： Shen, Quan ² ; Ren, Rongqing ⁴ ; Zhang, Wen ³ ; Yang, Zhibiao ¹ ; Yang, Shixing ¹ ; Chen, Yan ¹ ; Cui, Li ¹ ; Hua, Xiuguo ¹ ;

作者机构： 1.Shanghai Jiao Tong Univ, Shanghai Key Lab Vet Biotechnol, Sch Agr & Biol, Shanghai 200240, Peoples R China

2.Ohio State Univ, Ohio Agr Res & Dev Ctr, Food Anim Hlth Res Program, Wooster, OH 44691 USA

3.Jiangsu Univ, Sch Med Technol, Zhenjiang, Jiangsu, Peoples R China

4.Guizhou Acad Agr Sci, Guizhou Vet Res Inst, Guiyang, Guizhou, Peoples R China

关键词： Hepatitis E virus;Porcine;Caliciviruses;Genetic diversity

期刊名称：HEPATITIS MONTHLY （ 影响因子：0.66； 五年影响因子：1.409 ）

ISSN： 1735-143X

年卷期： 2011 年 11 卷 6 期

页码：

收录情况： SCI

摘要： Backgroud: Hepatitis E virus (HEV) and caliciviruses are enteric pathogens of humans and animals, and pigs have been considered an important reservoir of these viruses. Objectives: The aim of this study is to determine the infection rates of HEV and caliciviruses (sapovirus [Say] and norovirus [NoV]) in different age groups of pigs in Guizhou province, China, and characterize the strains that are prevalent in this mountainous area. Materials and Methods: A total of 209 stool samples from healthy pigs of different ages were collected from 6 pig farms in Guizhou province from May to June 2009 and tested for HEV, Say, and NoV by reverse-transcription polymerase chain reaction (RT-PCR). Results: The overall prevalence of porcine HEV and porcine Say was 6.7% (15/209) and 1.0% (2/209), respectively. No NoV was detected. The prevalence rates of porcine HEV infection were 15.4% in piglets aged <1 mon (4/26), 6.8% in piglets aged between 1 and 4 mon (3/44), 12.5% in piglets aged approximate to 4 mon (6/48), and 1.1% in sows aged between 6 and 14 mon (2/91). Porcine SaV was detected only in piglets (7.7%, 2/26). AUK) HEV isolates belonged to genotype 4, clustering with a human HEV strain (AF103940) from an adjacent province. Conclusions: This is the first report on the existence of porcine SaV in swine in Guizhou province, China. The clustering of the porcine HEV isolates with a human strain suggests cross-species transmission between swine and humans in this area. (C) 2011 Kowsar M.P.Co. All rights reserved.