文献类型： 会议论文

第一作者： Jiang-hong WU

作者： Jiang-hong WU ¹ ; Husile GONG ² ; Qing-jiang LUAN ¹ ; Ling XUE ³ ; Hai-lian SUN ¹ ; Feng WANG ¹ ;

作者机构： 1.Animal husbandry Institute, Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences

2.College of Animal Science, Inner Mongolia Agricultural University

3.Animal Husbandry Workstation of Duolun

关键词： Allele-specific gene expression;Coat color;Cattle;Transcriptome

会议名称： International Conference on Biological Sciences and Technology

主办单位：

页码： 114-125

摘要： Heterosis is a powerful and valuable tool for commercial beef producers, especially cow calf operations. Despite the importance of heterosis, and its extensive genetic analysis, little understanding exists of its molecular basis. We applied RNA-Seq technology to assess transcriptome-wide allele-specific gene expression (ASGE) in the hybrid genetic background at economic traits of offspring and maternal. 120 genes of these were different expression among three individuals in common. Among these genes, we found that three genes involved in melanogenesis pathway, including MC1R, DCT and TYR. In addition six of the altered expression genes were related to arachidonic acid (AA) metabolism, such as PTGS1, PTGIS, PTGR1, ALOX12B, ALOX15B and EPHX2. We find that coat color traits could be utilized to check the analysis pipeline for heterosis studies. Results from this study indicate that the parental alleles have un-equivalent functions in the hybrid, which may have an impact on heterosis.

分类号： Q81-53