文献类型： 会议论文

第一作者： M.B. Nottle

作者： M.B. Nottle ¹ ; L.F.S. Beebe; S.J. Harrison; R.A. Faast;

作者机构： 1.Reproductive Biotechnology Division, BresaGen Limited, PO Box 259, Rundle Mall, SA 5005

会议名称： Manipulating pig production IX

主办单位：

页码： 43-49

摘要： During the past two decades there has been considerable interest in the improvement of existing reproductive technologies as well as the development of new ones for the pig industry. This has been brought about by a consolidation in the pig industry worldwide and an increased interest in using pigs for various biomedical applications. During the past 10 years we have witnessed the production of piglets using sexed semen from frozen, thawed embryos and more recently cloned pigs using somatic cell nuclear transfer. The rate at which these and other reproductive technologies are adopted will be increased by the recent development of non-surgical methods for deep uterine insemination and embryo transfer. In particular, the development of cloning technology is advancing at a rapid rate. The power of this technology lies not only in its ability to disseminate an elite animal's genetics at a much greater rate than is currently possible, using AI for example, but also in its ability to allow the porcine genome to be manipulated precisely for the first time. This, together with the development of mammalian artificial chromosomes as vectors for introducing large transgenes, gene clusters and chromosomal segments will allow us to explore the full potential of this equally powerful technology. These technologies, together with the ability to freeze these genetics either as cells or embryos, will change the way pig genetics are disseminated in the future.

分类号： S828