1Fecal Microbiota Was Reshaped in UCP1 Knock-In Pigs via the Adipose-Liver-Gut Axis and Contributed to Less Fat Deposition

作者： Pan, Jianfei; Chui, Linya; Liu, Xuexue; Liu, Lulu; Zhao, Ying; Zhang, Lilan; Song, Min; Tang, Chaohua; Tao, Cong; Wang, Yanfang; Chui, Linya; Huang, Jiaojiao; Liu, Tianxia; Zheng, Qiantao; Zhao, Jianguo; Song, Min; Han, Jianlin; Han, Jianlin; SCI

机构： Chinese Acad Agr Sci, Inst Anim Sci, State Key Lab Anim Nutr, Beijing, Peoples R China; Qingdao Agr Univ, Coll Anim Sci & Technol, Qingdao, Peoples R China; Chinese Acad Sci, Inst Zool, State Key Lab Stem Cell & Reprod Biol, Beijing, Peoples R China; Chinese Acad Agr Sci CAAS, Inst Anim Sci, CAAS ILRI Joint Lab Livestock & Forage Genet Resou, Beijing, Peoples R China; Int Livestock Res Inst ILRI, Livestock Genet Program, Nairobi, Kenya;

来源：MICROBIOLOGY SPECTRUM

关键词： UCP1; fecal microbiota; HDCA; adipose tissue; pig

年份：2023

2Thyroid hormone regulates hematopoiesis via the TR-KLF9 axis

作者： Zhang, Ying; Cao, Chunwei; Huang, Jiaojiao; Hong, Qianlong; Hai, Tang; Jia, Qitao; Wang, Xianlong; Qin, Guosong; Yao, Jing; Wang, Xiao; Zheng, Qiantao; Zhang, Rui; Li, Yongshun; Luo, Ailing; Zhang, Nan; Wang, Hongmei; Zhou, Qi; Zhao, Jianguo; Zhang, Ying; Xue, Yuanyuan; Wang, Hongmei; Zhou, Qi; Liu, Feng; Zhao, Jianguo; Zhang, Ying; Cao, Chunwei; Huang, Jiaojiao; Hong, Qianlong; Hai, Tang; Jia, Qitao; Wang, Xianlong; Qin, Guosong; Yao, Jing; Wang, Xiao; Zheng, Qiantao; Zhang, Rui; Li, Yongshun; Luo, Ailing; Zhang, Nan; Liu, Zhonghua; Wang, Hongmei; Meng, Anming; Zhou, Qi; Wei, Hong; Zhao, Jianguo; Xue, Yuanyuan; Liu, Feng; Shi, Guizhi; Wang, Yanfang; Ying, Hao; Liu, Zhonghua; Meng, Anming; Wei, Hong; SCI

机构： Chinese Acad Sci, Inst Zool, State Key Lab Stem Cell & Reprod Biol, 1 Beichen West Rd, Beijing 100101, Peoples R China; Chinese Acad Sci, Inst Zool, State Key Lab Stem Cell & Reprod Bi;

来源：BLOOD

年份：2017

3CRISPR editing in biological and biomedical investigation

作者： Huang, Jiaojiao; Zhao, Jianguo; Wang, Yanfang; Zhao, Jianguo; SCI

机构： Chinese Acad Sci, Inst Zool, State Key Lab Stem Cell & Reprod Biol, Beijing 100101, Peoples R China; Chinese Acad Agr Sci, Inst Anim Sci, Beijing, Peoples R China; Univ Chinese Acad Sci, Savaid Med Sch, Beijing, Peoples R China;

来源：JOURNAL OF CELLULAR PHYSIOLOGY

关键词： base editing CRISPR Cas gene therapy human diseases models transcriptional regulation

年份：2018

4Efficient CRISPR/Cas9-mediated biallelic gene disruption and site-specific knockin after rapid selection of highly active sgRNAs in pigs

作者： Wang, Xianlong; Cao, Chunwei; Huang, Jiaojiao; Hai, Tang; Zheng, Qiantao; Zhang, Hongyong; Qin, Guosong; Miao, Xiangnan; Wang, Hongmei; Zhou, Qi; Zhao, Jianguo; Zhou, Jinwei; Cao, Suizhong; Huang, Jiaojiao; Zheng, Qiantao; Zhang, Hongyong; Wang, Hongmei; Zhou, Qi; Zhao, Jianguo; Wang, Yanfang; SCI

机构： Chinese Acad Sci, Inst Zool, State Key Lab Reprod Biol, Beijing 100101, Peoples R China; Sichuan Agr Univ, Coll Vet Med, Yaan 625014, ;

来源：SCIENTIFIC REPORTS

年份：2015

5One-step generation of triple gene-targeted pigs using CRISPR/Cas9 system

作者： Wang, Xianlong; Cao, Chunwei; Huang, Jiaojiao; Yao, Jing; Hai, Tang; Zheng, Qiantao; Wang, Xiao; Zhang, Hongyong; Qin, Guosong; Zhou, Qi; Wang, Hongmei; Zhao, Jianguo; Zheng, Qiantao; Wang, Xiao; Zhang, Hongyong; Zhou, Qi; Wang, Hongmei; Zhao, Jianguo; Cheng, Jinbo; Yuan, Zengqiang; Wang, Yanfang; SCI

机构： Chinese Acad Sci, Inst Zool, State Key Lab Stem Cell & Reprod Biol, Beijing 100101, Peoples R China; Chinese Acad S;

来源：SCIENTIFIC REPORTS

年份：2016

6Reconstitution of UCP1 using CRISPR/Cas9 in the white adipose tissue of pigs decreases fat deposition and improves thermogenic capacity

作者： Zheng, Qiantao; Huang, Jiaojiao; Zhang, Hongyong; Zhang, Rui; Cao, Chunwei; Qin, Guosong; Yao, Jing; Song, Ruigao; Jia, Qitao; Wang, Xiao; Li, Yongshun; Zhang, Nan; Wang, Hongmei; Zhou, Qi; Zhao, Jianguo; Zheng, Qiantao; Huang, Jiaojiao; Zhang, Hongyong; Zhang, Rui; Cao, Chunwei; Qin, Guosong; Yao, Jing; Song, Ruigao; Jia, Qitao; Wang, Xiao; Wang, Hongmei; Zhou, Qi; Jin, Wanzhu; Zhao, Jianguo; Lin, Jun; Song, Ruigao; Ye, Rongcai; Jin, Wanzhu; Lin, Jun; Ye, Rongcai; Zhang, Xueying; Speakman, John R.; Hambly, Catherine; Speakman, John R.; Piao, Zhengyu; Wang, Yanfang; SCI

机构： Chinese Acad Sci, State Key Lab Stem Cell & Reprod Biol, Beijing 100101, Peoples R China; Chinese Acad Sci, State Key Lab St;

来源：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

关键词： UCP1 thermoregulation fat deposition pig CRISPR/Cas9

7PPAR gamma is regulated by miR-27b-3p negatively and plays an important role in porcine oocyte maturation

作者： Song, Chunlei; Liang, Xiaojuan; Tao, Cong; Li, Kui; Wang, Yanfang; Yao, Jing; Cao, Chunwei; Huang, Jiaojiao; Han, Ziqiang; Zhang, Yang; Qin, Guosong; Zhao, Jianguo; Yao, Jing; Cao, Chunwei; Huang, Jiaojiao; Zhang, Yang; Qin, Guosong; Zhao, Jianguo; Han, Ziqiang; Li, Chengbo; Yang, Haoran; SCI

机构： Chinese Acad Agr Sci, Inst Anim Sci, State Key Lab Anim Nutr, Beijing 100081, Peoples R China; Chinese Acad Sci, State Key Lab Reprod Biol, Inst Zool, Beijing 100101, Peoples R China; Chinese Acad Sc;

来源：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

关键词： Pig miRNA Oocyte maturation PPAR gamma Fatty acid metabolism

8The asynchronous establishment of chromatin 3D architecture between in vitro fertilized and uniparental preimplantation pig embryos

作者： Li, Feifei; Wang, Danyang; Zhang, Zhihua; Li, Xiaoli; Xu, Bingxiang; Li, Xiao; Gao, Xiaomeng; Jia, Yan; Li, Feifei; Wang, Danyang; Zhang, Zhihua; Li, Xiaoli; Xu, Bingxiang; Li, Xiao; Gao, Xiaomeng; Jia, Yan; Wang, Danyang; Song, Ruigao; Zhang, Zhihua; Li, Xiaoli; Xu, Bingxiang; Li, Xiao; Gao, Xiaomeng; Zhao, Jianguo; Song, Ruigao; Wang, Yu; Huang, Jiaojiao; Liu, Qiang; Hou, Naipeng; Zhao, Jianguo; Cao, Chunwei; Cao, Chunwei; Wang, Yu; Hou, Naipeng; Wang, Yanfang; SCI

机构： Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China; China Natl Ctr Bioinformat, Beijing 100101, Peoples R China; Univ Chinese Acad Sci, Beijing 100049, Peoples R China; Chinese Acad Sci, Inst Zool, State Key Lab Stem Cell & Reprod Biol, Beijing, Peoples R China; Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Med Res Ctr, Guangdong Prov Key Lab Malignant Tumor Epigenet &, Guangzhou 510120, Peoples R China; Chinese Acad Agr Sci, Inst Anim Sci, Beijing 100193, Peoples R China;

来源：GENOME BIOLOGY

关键词： Pig; Early embryos; Chromatin 3D architecture; In vitro fertilization; Parthenogenesis; Androgenesis

年份：2020

9Differential Analysis of Fecal SCFAs and Their Contribution to Adipogenesis in UCP1 Knock-In Pigs

作者： Zhao, Chengyu; Huang, Jiaojiao; Zhao, Chengyu; Huang, Jiaojiao; Zhao, Chengyu; Pan, Jianfei; Wang, Yanfang; Zhao, Jianguo; SCI

机构： Qingdao Agr Univ, Coll Anim Sci & Technol, Qingdao 266109, Peoples R China; Qingdao Agr Univ, Coll Life Sci, Qingdao 266109, Peoples R China; Chinese Acad Agr Sci, Inst Anim Sci, State Key Lab Anim Biotech Breeding, Beijing 100193, Peoples R China; Chinese Acad Sci, State Key Lab Stem Cell & Reprod Biol, Inst Zool, Beijing 100101, Peoples R China;

来源：VETERINARY SCIENCES

关键词： pigs; UCP1; SCFAs; caproic acid; fat deposition; gut microbiota

年份：2025

10Single-nucleus RNA sequencing defines adipose tissue subpopulations that contribute to Tibetan pig cold adaptation

作者： Liu, Jiali; Chen, Chuanhe; Chui, Linya; Zhang, Xueping; Wang, Xiao; Yang, Chunhuai; Wu, Tianwen; Yang, Shulin; Tao, Cong; Wang, Yanfang; Jiang, Yao; Liu, Tianxia; Cui, Along; Zhang, Xueping; Wang, Yu; Zhang, Ying; Zhao, Jianguo; Liu, Tianxia; Wang, Yu; Zhao, Jianguo; Liu, Tianxia; Cui, Along; Wang, Yu; Zhang, Ying; Zhao, Jianguo; Zhang, Ying; Zhao, Jianguo; Cui, Along; Zhang, Xueping; Chui, Linya; Huang, Jiaojiao; Zhao, Jianguo; Wang, Yanfang; SCI

机构： Chinese Acad Agr Sci CAAS, Inst Anim Sci, State Key Lab Anim Biotech Breeding, Beijing 100193, Peoples R China; Natl Anim Husb Serv, Beijing 100125, Peoples R China; Chinese Acad Sci, Inst Zool, State Key Lab Stem Cell & Reprod Biol, Beijing 100101, Peoples R China; Univ Chinese Acad Sci, Beijing 100049, Peoples R China; Chinese Acad Sci, Lnstitute Stem Cell & Regenerat, Beijing 100101, Peoples R China; Beijing Inst Stem Cell & Regenerat Med, Beijing 100101, Peoples R China; Univ Sci & Technol China, Div Life Sci & Med, Hefei 230026, Peoples R China; Gansu Agr Univ, Coll Anim Sci & Technol, Lanzhou 730070, Peoples R China; Qingdao Agr Univ, Coll Life Sci, Qingdao 266109, Peoples R China; Hainan Acad Agr Sci, Sanya Inst, Sanya 572025, Peoples R China;

来源：BMC BIOLOGY

关键词： Pig; snRNA-seq; Adipocytes; Subpopulations; Cold stimulation

年份：2025