1Nucleosome-Omics: A Perspective on the Epigenetic Code and 3D Genome Landscape

作者： Kong, Siyuan; Lu, Yuhui; Tan, Shuhao; Li, Rongrong; Gao, Yan; Li, Kui; Zhang, Yubo; SCI

机构： Chinese Acad Agr Sci, Agr Genom Inst Shenzhen,Shenzhen Branch, Anim Funct Genom Grp,Guangdong Lab Lingnan Modern, Minist Agr & Rural Affairs,Genome Anal Lab,Key La, Shenzhen 518120, Peoples R China;

来源：GENES

关键词： epigenetics; nucleosomes; MNase-seq; Micro-C; 3D genome

年份：2022

2A single-cell genomic strategy for alternative transcript start sites identification

作者： Peng, Yanling; Huang, Qitong; Liu, Danli; Kong, Siyuan; Zhang, Yubo; Huang, Qitong; Kamada, Rui; Ozato, Keiko; Zhang, Yubo; Zhu, Jun; Zhang, Yubo; Zhu, Jun; SCI

机构： Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Guangdong Lab Lingnan Modern Agr Genome Anal Lab, Anim Funct Genom Grp,Shenzhen Branch,Minist Agr, Shenzhen, Peoples R China; Wageningen Univ & Res, Anim Breeding & Genom, Wageningen, Netherlands; Hokkaido Univ, Fac Sci, Dept Chem, Sapporo, Hokkaido, Japan; NICHHD, Div Dev Biol, NIH, Bethesda, MD USA; Kunpeng Inst Modern Agr Foshan, Foshan, Peoples R China; NHLBI, DNA Sequencing & Genom Core, NIH, Bethesda, MD USA; Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Guangdong Lab Lingnan Modern Agr Genome Anal Lab, Anim Funct Genom Grp,Shenzhen Branch,Minist Agr, Shenzhen 518120, Peoples R China; NHLBI, DNA Sequencing & Genom Core, NIH, Bethesda, MD 20892 USA;

来源：BIOTECHNOLOGY JOURNAL

关键词： analytical biotechnology; bioinformatics

年份：2024

3MAE-seq refines regulatory elements across the genome

作者： Zhu, Xiusheng; Huang, Qitong; Huang, Lei; Luo, Jing; Li, Qing; Kong, Dashuai; Deng, Biao; Gu, Yi; Wang, Xueyan; Li, Chenying; Kong, Siyuan; Zhang, Yubo; Huang, Qitong; Zhang, Yubo; SCI

机构： Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Key Lab Livestock & Poultry Multi MARA, Shenzhen Branch,Guangdong Lab Lingnan Modern Agr, Shenzhen 518120, Peoples R China; Wageningen Univ & Res, Dept Anim Sci, NL-6708PB Wageningen, Netherlands; Kunpeng Inst Modern Agr Foshan, Foshan 528225, Peoples R China;

来源：NUCLEIC ACIDS RESEARCH

年份：2023

4Single-cell omics: A new direction for functional genetic research in human diseases and animal models

作者： Kong, Siyuan; Li, Rongrong; Tian, Yunhan; Zhang, Yaqiu; Lu, Yuhui; Ou, Qiaoer; Gao, Peiwen; Li, Kui; Zhang, Yubo; Kong, Siyuan; Tian, Yunhan; Li, Kui; Zhang, Yubo; Zhang, Yubo; SCI

机构： Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Guangdong Lab Lingnan Modern Agr, Shenzhen Branch,Key Lab Livestock & Poultry Multi, Shenzhen, Peoples R China; Qingdao Agr Univ, Coll Anim Sci & Technol, Qingdao, Peoples R China; Foshan Univ, Coll Life Sci & Engn, Foshan, Peoples R China;

来源：FRONTIERS IN GENETICS

关键词： single-cell omics; multi-omics integration; human disease; cell lines; animal disease models

年份：2023

5Genetic characteristics of polycistronic system-mediated randomly-inserted multi-transgenes in miniature pigs and mice

作者： Kong, Siyuan; Li, Li; Zhu, Wenjuan; Xin, Leilei; Ruan, Jinxue; Yang, Shulin; Li, Kui; Kong, Siyuan; Zhang, Yubo; Li, Kui; SCI

机构： Chinese Acad Agr Sci, Inst Anim Sci, Key Lab Farm Anim Genet Resource & Germplasm Inno, State Key Lab Anim Nutr,Minist Agr, 2 Yuanmingyuan West Rd, Beijing 100193, Peoples R China; Chinese Acad Agr Sci, Inst Anim Sci, Key Lab Farm Anim Genet Resource & Germplasm Inno, State Key Lab Anim Nutr,Minist ;

来源：MOLECULAR MEDICINE REPORTS

关键词： multi-transgene miniature pig mice copy number experimental animal disease model

年份：2018

6Kill two birds with one stone: making multi-transgenic pre-diabetes mouse models through insulin resistance and pancreatic apoptosis pathogenesis

作者： Kong, Siyuan; Ruan, Jinxue; Zhang, Kaiyi; Hu, Bingjun; Cheng, Yuzhu; Yang, Shulin; Li, Kui; Kong, Siyuan; Ruan, Jinxue; Zhang, Kaiyi; Hu, Bingjun; Cheng, Yuzhu; Yang, Shulin; Li, Kui; Kong, Siyuan; Zhang, Yubo; Li, Kui; SCI

机构： Chinese Acad Agr Sci, Inst Anim Sci, Minist Agr, State Key Lab Anim Nutr, Beijing, Beijing, Peoples R China; Chinese Acad Agr Sci, Inst Anim Sci, Minist Agr, Key Lab Farm Anim Genet Resources & Germplasm Inn, Beijing, Beijing, Peoples R China; Chinese Acad Agr Sci, Inst Anim Sci, Minist Agr, Key Lab Farm Anim Genet Resources & Germplasm Inn, Beijing, Beijing, Peoples ;

来源：PEERJ

关键词： Muti-transgenic mice; Experiment animal disease model; 11 beta HSD-1; hIAPP; CHOP

年份：2018

7Deciphering Hi-C: from 3D genome to function

作者： Kong, Siyuan; Zhang, Yubo; SCI

机构： Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Anim Funct Genom Grp, 7 Pengfei Rd, Shenzhen 518120, Peoples R China;

来源：CELL BIOLOGY AND TOXICOLOGY

关键词： Hi-C; 3D genomics; Chromatin interaction; Transcription regulation; Gene function

年份：2019

8Exonuclease combinations reduce noises in 3D genomics technologies

作者： Kong, Siyuan; Li, Qing; Zhang, Gaolin; Li, Qiujia; Huang, Qitong; Huang, Lei; Peng, Yanling; Zhang, Yubo; Zhang, Hui; Huang, Yinghua; Qin, Baoming; SCI

机构： Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Guangdong Lab Lingnan Modern Agr Genome Anal Lab, Anim Funct Genom Grp,Shenzhen Branch,Minist Agr, Shenzhen 518120, Peoples R China; Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, CAS Key Lab Regenerat Biol, Guangdong Prov Key Lab Stem Cell & Regenerat Med, Guangzhou 510530, Peoples R China;

来源：NUCLEIC ACIDS RESEARCH

年份：2020