The unconventional resistance protein PTR recognizes the Magnaporthe oryzae effector AVR-Pita in an allele-specific manner

文献类型： 外文期刊

第一作者： Xiao, Gui

作者： Xiao, Gui;Wu, Jun;Xiao, Gui;Telebanco-Yanoria, Mary Jeanie;Zhou, Bo;Laksanavilat, Nutthalak;Cesari, Stella;Lambou, Karine;Baudin, Mael;Jalilian, Ahmad;Chalvon, Veronique;Meusnier, Isabelle;Fournier, Elisabeth;Tharreau, Didier;Kroj, Thomas;Tharreau, Didier;Baudin, Mael;Jalilian, Ahmad

作者机构：

期刊名称：NATURE PLANTS （ 影响因子：18.0； 五年影响因子：18.6 ）

ISSN： 2055-026X

年卷期： 2024 年

页码：

收录情况： SCI

摘要： Blast disease caused by the fungus Magnaporthe oryzae is one of the most devastating rice diseases. Disease resistance genes such as Pi-ta or Pi-ta2 are critical in protecting rice production from blast. Published work reports that Pi-ta codes for a nucleotide-binding and leucine-rich repeat domain protein (NLR) that recognizes the fungal protease-like effector AVR-Pita by direct binding. However, this model was challenged by the recent discovery that Pi-ta2 resistance, which also relies on AVR-Pita detection, is conferred by the unconventional resistance gene Ptr, which codes for a membrane protein with a cytoplasmic armadillo repeat domain. Here, using NLR Pi-ta and Ptr RNAi knockdown and CRISPR/Cas9 knockout mutant rice lines, we found that AVR-Pita recognition relies solely on Ptr and that the NLR Pi-ta has no role in it, indicating that it is not the Pi-ta resistance gene. Different alleles of Ptr confer different recognition specificities. The A allele of Ptr (PtrA) detects all natural sequence variants of the effector and confers Pi-ta2 resistance, while the B allele of Ptr (PtrB) recognizes a restricted set of AVR-Pita alleles and, thereby, confers Pi-ta resistance. Analysis of the natural diversity in AVR-Pita and of mutant and transgenic strains identified one specific polymorphism in the effector sequence that controls escape from PtrB-mediated resistance. Taken together, our work establishes that the M. oryzae effector AVR-Pita is detected in an allele-specific manner by the unconventional rice resistance protein Ptr and that the NLR Pi-ta has no function in Pi-ta resistance and the recognition of AVR-Pita.

分类号：

  • 相关文献
作者其他论文 更多>>
  • Oocytes maintain low ROS levels to support the dormancy of primordial follicles

    作者：Qin, Shaogang;Chi, Xinyue;Zhu, Zijian;Gao, Meng;Zhao, Ting;Zhang, Jingwen;Zheng, Wenying;Chen, Ziqi;Zhou, Bo;Xia, Guoliang;Wang, Chao;Chen, Chuanhe;Zhang, Tuo;He, Meina;Zhang, Lifan;Wang, Wenji

    关键词：ferroptosis; primary ovarian insufficiency; primordial follicle; ROS; SOD1

  • An opensource indoor climate and yield prediction model for Chinese solar greenhouses

    作者：Zhou, Bo;Wang, Nan;Yang, Qichang;Zhou, Bo;Wang, Nan;Yang, Qichang;Zhou, Bo;Lastiri, Daniel Reyes;van Henten, Eldert J.

    关键词：Chinese solar greenhouse; Climate model; Tomato yield prediction; Sensitivity analysis

  • Small G Protein OsRab6a Confers Cold Tolerance by Cooperating With OsRAN2 and Suppressing ABA Signalling in Rice

    作者：Li, Chenggang;Huang, Fenglin;Xie, Hongjun;Li, Chenggang;Huang, Fenglin;Xie, Hongjun;Li, Chenggang;Huang, Fenglin;Xie, Hongjun;Chen, Yue;Xiao, Yinghui;Jiang, Su;He, Huqiang;Huang, Shipeng;Li, Guangzhao;Chen, Chuanxin;Sun, Yuancheng;Wu, Jun;Wang, Dan;Chen, Rubin;Xiao, Yinghui;Jiang, Su;He, Huqiang;Huang, Shipeng;Li, Guangzhao;Chen, Chuanxin;Sun, Yuancheng;Wu, Jun;Wang, Dan;Chen, Rubin;Chen, Yue

    关键词：cold tolerance; Oryza Sativa. L; OsRab6a; OsRAN2; small-GTP protein

  • Integrating large-scale meta-GWAS and PigGTEx resources to decipher the genetic basis of 232 complex traits in pigs

    作者：Xu, Zhiting;Lin, Qing;Cai, Xiaodian;Zhong, Zhanming;Teng, Jinyan;Zeng, Haonan;Gao, Yahui;Wei, Chen;Zhou, Jun;Zhang, Wenjing;Zhang, Xiaoke;Shi, Shaolei;Wu, Jun;Diao, Shuqi;Liu, Yuqiang;Pan, Xiangchun;Feng, Xueyan;Liu, Ruiqi;Su, Zhanqin;Chang, Chengjie;Zhu, Qianghui;Wu, Yuwei;Zhang, Hao;Yuan, Xiaolong;Li, Jiaqi;Zhang, Zhe;Li, Bingjie;Gao, Yahui;Liu, George E.;Gao, Yahui;Ma, Li;Cai, Zexi;Bai, Zhonghao;Su, Guosheng;Sahana, Goutam;Lund, Mogens Sando;Fang, Lingzhao;Wang, Xiaoqing;Shi, Liangyu;Zhao, Fuping;Wang, Xue;Wang, Yi;Zhang, Zipeng;Ding, Xiangdong;Lin, Yu;Tang, Guoqing;Li, Mingzhou;Li, Xuewei;Liu, Shuli;Yin, Hongwei;Bai, Lijing;Li, Kui;Zhou, Zhongyin;Wang, Qishan;Pan, Yuchun;Xu, Zhong;Peng, Xianwen;Mei, Shuqi;Mo, Delin;Liu, Xiaohong;Chen, Yaosheng;Liu, Yang;Xiang, Ruidong;Xiang, Ruidong;Shen, Xia;Shen, Xia;Shen, Xia;Li, Pinghua;Huang, Ruihua;Li, Pinghua;Huang, Ruihua;Ballester, Maria;Crespo-Piazuelo, Daniel;Amills, Marcel;Clop, Alex;Amills, Marcel;Karlskov-Mortensen, Peter;Fredholm, Merete;Zhang, Qin;Zhao, Yunxiang

    关键词：pig; meta-GWAS; PigGTEx; molQTL; complex traits

  • Research note: Unveiling the impact of ovotransferrin on chicken primordial germ cells biological processes

    作者：Liu, Xin;Peng, Yixiu;Wu, Jun;Qian, Hongwu;Lv, Xiaoqian;Li, Fan;Jin, Kai;Niu, Yingjie;Chen, Guohong;Li, Bichun;Zuo, Qisheng;Liu, Xin;Peng, Yixiu;Wu, Jun;Qian, Hongwu;Lv, Xiaoqian;Li, Fan;Jin, Kai;Niu, Yingjie;Chen, Guohong;Li, Bichun;Zuo, Qisheng;Liu, Xin;Peng, Yixiu;Wu, Jun;Qian, Hongwu;Lv, Xiaoqian;Li, Fan;Jin, Kai;Niu, Yingjie;Chen, Guohong;Li, Bichun;Zuo, Qisheng;Song, Jiuzhou;Han, Wei;Li, Bichun

    关键词：Chicken; Primordial germ cell; ovotransferrin; chicken; serum

  • Characterization of a KANADI-like transcription factor that suppresses pear anthocyanin biosynthesis

    作者：Wei, Weilin;Chen, Guosong;Cao, Beibei;Qin, Mengfan;Wang, Runze;Li, Jiaming;Wu, Jun;Lin-Wang, Kui;Espley, Richard, V;Allan, Andrew C.;Sha, Shoufeng;Li, Juncai

    关键词：

  • Bacillus paralicheniformis SYN-191 isolated from ginger rhizosphere soil and its growth-promoting effects in ginger farming

    作者：Sun, Yanan;Liu, Kai;Liu, Yayu;Yang, Xuerong;Du, Binghai;Li, Xiang;Zhou, Bo;Wang, Chengqiang;Liu, Zhongliang;Li, Ningyang;Li, Ningyang;Zhu, Xueming;Wang, Hailong;Peng, Bingyin

    关键词：Ginger; Continuous cropping; Bacillus paralicheniformis; Plant-microbial interaction; Whole genome analysis

微信小程序