文献类型： 外文期刊
第一作者： Wang, Fu
作者： Wang, Fu;Zang, Zhenyuan;Zhao, Qian;Xiaoyang, Chunxiao;Ma, Yiqiao;Zhang, Jian;Lei, Xiujuan;Wang, Yingping;Cao, Rongan;Zhang, Jian;Song, Xixia;Tang, Lili;Deyholos, Michael K.
作者机构：
关键词： Cannabidiol (CBD); cannabinoid; biosynthesis; metabolic engineering; synthetic biology
期刊名称：ACS SYNTHETIC BIOLOGY （ 影响因子：3.7； 五年影响因子：4.2 ）
ISSN： 2161-5063
年卷期： 2024 年 13 卷 7 期
页码：
收录情况： SCI
摘要： Cannabis sativa L. is a multipurpose crop with high value for food, textiles, and other industries. Its secondary metabolites, including cannabidiol (CBD), have potential for broad application in medicine. With the CBD market expanding, traditional production may not be sufficient. Here we review the potential for the production of CBD using biotechnology. We describe the chemical and biological synthesis of cannabinoids, the associated enzymes, and the application of metabolic engineering, synthetic biology, and heterologous expression to increasing production of CBD.
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