Carbazomycins I and J, two novel carbazole alkaloids isolated from Saccharopolyspora phattalungensis
文献类型： 外文期刊
第一作者： Wang, Wen
作者： Wang, Wen;Zhao, Er Juan;Peng, Ting;Yan, Zhang Yuan;Jiao, Rui Hua;Guo, Zhi Kai;Guo, Zhi Kai
作者机构：
关键词： Microbial Natural Products; Carbazole alkaloids; Structural elucidation; Gene cluster; Biosynthesis pathway
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.7； 五年影响因子：1.8 ）
ISSN： 1874-3900
年卷期： 2024 年 60 卷
页码：
收录情况： SCI
摘要： Carbazomycins I (1) and J (2), two novel carbazole alkaloids were isolated from the fermentation broth of Saccharopolyspora phattalungensis DSM 45584. Their structures were elucidated by analysis of HRESIMS and NMR spectroscopic data. Compounds 1 and 2 were evaluated for their antimicrobial activities against seven pathogens by the agar diffusion method. Additionally, bioinformatics analysis revealed the biosynthetic gene cluster for carbazomycins (1) and J (2).
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