Carbazomycins I and J, two novel carbazole alkaloids isolated from Saccharopolyspora phattalungensis

文献类型: 外文期刊

第一作者: Wang, Wen

作者: Wang, Wen;Zhao, Er Juan;Peng, Ting;Yan, Zhang Yuan;Jiao, Rui Hua;Guo, Zhi Kai;Guo, Zhi Kai

作者机构:

关键词: Microbial Natural Products; Carbazole alkaloids; Structural elucidation; Gene cluster; Biosynthesis pathway

期刊名称:PHYTOCHEMISTRY LETTERS ( 影响因子:1.7; 五年影响因子:1.8 )

ISSN: 1874-3900

年卷期: 2024 年 60 卷

页码:

收录情况: SCI

摘要: Carbazomycins I (1) and J (2), two novel carbazole alkaloids were isolated from the fermentation broth of Saccharopolyspora phattalungensis DSM 45584. Their structures were elucidated by analysis of HRESIMS and NMR spectroscopic data. Compounds 1 and 2 were evaluated for their antimicrobial activities against seven pathogens by the agar diffusion method. Additionally, bioinformatics analysis revealed the biosynthetic gene cluster for carbazomycins (1) and J (2).

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