Plant synthetic genomics: Big lessons from the little yeast

文献类型： 外文期刊

第一作者： Ye, Hao

作者： Ye, Hao;Luo, Guangyu;Zheng, Zhenwu;Li, Xiaofang;Cao, Jie;Liu, Jia;Dai, Junbiao;Luo, Guangyu;Dai, Junbiao

作者机构：

期刊名称：CELL CHEMICAL BIOLOGY （ 影响因子：7.2； 五年影响因子：8.7 ）

ISSN： 2451-9456

年卷期： 2024 年 31 卷 10 期

页码：

收录情况： SCI

摘要： Yeast has been extensively studied and engineered due to its genetic amenability. Projects like Sc2.0 and Sc3.0 have demonstrated the feasibility of constructing synthetic yeast genomes, yielding promising results in both research and industrial applications. In contrast, plant synthetic genomics has faced challenges due to the complexity of plant genomes. However, recent advancements of the project SynMoss, utilizing the model moss plant Physcomitrium patens, , offer opportunities for plant synthetic genomics. The shared characteristics between P. patens and yeast, such as high homologous recombination rates and dominant haploid life cycle, enable researchers to manipulate P. patens genomes similarly, opening promising avenues for research and application in plant synthetic biology. In conclusion, harnessing insights from yeast synthetic genomics and applying them to plants, with P. patens as a breakthrough, shows great potential for revolutionizing plant synthetic genomics.

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