Penisarins A and B, Sesquiterpene Coumarins Isolated from an Endophytic Penicillium sp.
文献类型: 外文期刊
第一作者: Li, Wei
作者: Li, Wei;Shao, Ya-Ting;Shen, Bao-Chun;Li, Yuan-Yi;Xie, Hui-Ding;Sun, Zhong-Wen;Ma, Yu-Lu;Li, Wei;Shao, Ya-Ting;Shen, Bao-Chun;Li, Yuan-Yi;Xie, Hui-Ding;Sun, Zhong-Wen;Ma, Yu-Lu;Yin, Tian-Peng;Yan, Hui
作者机构:
期刊名称:JOURNAL OF NATURAL PRODUCTS ( 影响因子:4.05; 五年影响因子:4.603 )
ISSN: 0163-3864
年卷期: 2020 年 83 卷 11 期
页码:
收录情况: SCI
摘要: Penisarins A (1) and B (2), sesquiterpene coumarins with an unusual tricyclic sesquiterpene system, were isolated from endophytic Penicillium sp. KMU18029. Their structures were elucidated on the basis of spectroscopic methods, single-crystal X-ray diffraction, and electronic circular dichroism calculations. Compound 2 showed significant cytotoxicities against two human cancer cell lines, HL-60 and SMMC-7721, with IC50 values of 3.6 +/- 0.2 and 3.7 +/- 0.2 mu M, respectively.
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